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Previous research has suggested an association between phthalate exposure and depressive symptoms, but the evidence is limited. Our study aimed to examine the association between phthalate exposure and the risk of depressive symptoms in the US adult population. We used data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018 to analyze the association between urinary phthalates and depressive symptoms. We included 11 urinary phthalate metabolites in our analysis and used the 9-item Patient Health Questionnaire (PHQ-9) to assess the presence of depression among study participants. Participants were divided into quartiles for each urinary phthalate metabolite, and we evaluated the association using a generalized linear mixed model with a logit link and binary distribution. A total of 7340 participants were included in the final analysis. After controlling for potential confounders, we found a positive association between the molar sum of di (2-ethylhexyl) phthalate (DEHP) metabolites and depressive symptoms, with an odds ratio of 1.30 (95% CI = 1.02-1.66) for the highest compared to the lowest quartile. In addition, we found positive associations of mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) and mono (2-ethyl-5-carboxypentyl) phthalate (MECPP) with depressive symptoms, with odds ratios of 1.43 (95% CI = 1.12-1.81, p for trend = 0.02) and 1.44 (95% CI = 1.13-1.84, p for trend = 0.02), respectively, when comparing the highest quartile to the lowest quartile.. In conclusion, this study is the first to identify a positive association between DEHP metabolites and the risk of depressive symptoms in the general adult population in the United States., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Ming-Chieh Li reports a relationship with National Science and Technology Council that includes: funding grants., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Heavy metal pollution in urban soils and dust is mostly caused by extensive anthropogenic activity during urbanization and industrialization. In this research study, the pollution characteristics, sources, ecological and human health risks of heavy metals in urban soil, and dust have been thoroughly evaluated. The research findings demonstrate that dust has a higher level of contamination than urban soil, such as Pb, Cu, and Zn metals are more contaminated in both urban soil and dust throughout the city, and Hg and As are also found in locations with a high concentration of heavy industrial companies. This implies that traffic emissions are still a significant source of metals in urban areas, though industrial companies also contribute. The health risk assessment model used to calculate human exposure revealed that the non-carcinogenic and carcinogenic risks of selected metals in soil and dust were generally in the low range, except for the carcinogenic risk from Cr in children. Statistical analysis revealed that Cr and Ni concentrations were mainly of natural origin, Cu and Zn have been sourced from traffic, whereas Pb, Hg, and As have been sourced from industrial activities. The overall recommendation is that the road traffic environment and municipal construction facilities need to be improved to ensure the sustainable development of the city's environment, while pollution from industrial waste is strongly controlled., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Pollution caused by fine dust is becoming a global problem in the aquatic environment. Many studies have investigated the hazards that fine dust may pose to terrestrial organisms; however, information on the effects on aquatic environments remain limited. In this study, the physicochemical characteristics of the fine dust associated with the captured powder or liquid state were compared using scanning electron microscopy (SEM) and energy dispersive X-ray spectrometry (EDS). Raw fine dust (RFD), in the captured powder state, was suspended in water (SFD), and the elemental composition, morphology, and size distribution of both were analyzed. Zebrafish were used as a model to study the effects of SFD-exposure on aquatic organisms. A fatal malformation was observed in the integuments of zebrafish exposed to SFD, specifically in the exterior and interior eye tissues. Furthermore, the exposure of SFD to Tg (flk; EGFP) zebrafish remarkably increased ocular vessel diameter expansion along with blood flow velocity. Regarding vessel diameter expansion, EA.hy926 cells exposed to SFD were adversely affected, with a significant increase in cell migration and capillary-like structure formation, which are angiogenic markers. The SFD-induced angiogenesis in vitro and in vivo was dramatically restored to normal via α/β-adenosine isolated from the anti-angiogenic brown algae Ishige okamurae extract. Taken together, the current study presents solid evidence of the altered physicochemical characteristics of SFD compared to RFD, and the detrimental impact of SFD in an aquatic in vivo zebrafish model. In addition, the protective effect of α/β-adenosine, a marine natural product, on SFD-induced angiogenesis suggests that it can be used as an agent to reduce the adverse effects of SFD on aquatic animals., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Adsorption of trace organic compounds (TrOCs) onto the membrane materials has a great impact on their rejection by nanofiltration (NF) and reverse osmosis (RO) membranes. This study aimed to investigate the difference in adsorption of various pharmaceuticals (PhACs) onto different NF/RO membranes and to demonstrate the necessity of isolating the polyamide (PA) active layer from the polysulfone (PS) support layer for adsorption characterization and quantification. Both the isolated PA layers and the PA+PS layers of NF90 and ESPA1 membranes were used to conduct static adsorption tests. Results showed that apparent differences existed between the PA layer and the PA+PS layer in the adsorption capacity of PhACs as well as the time necessary to reach the adsorption equilibrium. PhACs with different physicochemical properties could be adsorbed to different extents by the isolated PA layer, which was mainly attributed to electrostatic attraction/repulsion and hydrophobic interactions. The PA layer of ESPA1 exhibited apparently higher adsorption capacities for the positively charged PhACs and similar adsorption capacities for the neutral PhACs although it had significantly less total interfacial area (per unit membrane surface area) for adsorption compared to the PA layer of NF90. The higher affinity of the PA layer of ESPA1 for the PhACs could be due to its higher capacity of forming hydrogen bonds with PhACs resulted from the modified chemistry with more -OH groups. This study provides a novel approach to determining the TrOC adsorption onto the active layer of membranes for the ease of investigating adsorption mechanisms., (Copyright © 2018 Elsevier Ltd. All rights reserved.)

A detailed kinetic model comprised of mass transport (k tra ), pore diffusion (k dif ), adsorption and reduction reaction (k rea ), was developed to quantitatively evaluate the effect of corrosion films on the removal rate (k obs ) of halogenated compounds by metallic iron. Different corrosion conditions were controlled by adjusting the iron aging time (0 or 1 yr) and dissolved oxygen concentration (0-7.09 mg/L DO). The k obs values for bromate, mono-, di- and tri-chloroacetic acids (BrO 3 - , MCAA, DCAA and TCAA) were 0.41-7.06, 0-0.16, 0.01-0.53, 0.10-0.73 h -1 , with k tra values at 13.32, 12.12, 11.04 and 10.20 h -1 , k dif values at 0.42-5.82, 0.36-5.04, 0.30-4.50, 0.30-3.90 h -1 , and k rea values at 14.94-421.18, 0-0.19, 0.01-1.30, 0.10-3.98 h -1 , respectively. The variation of k obs value with reaction conditions depended on the reactant species, while those of k tra , k dif and k rea values were irrelevant to the species. The effects of corrosion films on k dif and k rea values were responsible for the variation of k obs value for halogenated compounds. For a mass-transfer-limited halogenated compound such as BrO 3 - , an often-neglected k dif value primarily determined its k obs value when pore diffusion was the rate-limiting step of its removal. In addition, the value of k dif might influence product composition during a consecutive dechlorination, such as for TCAA and DCAA. For a reaction-controlled compound such as MCAA, an increased k rea value was achieved under low oxic conditions, which was favorable to improve its k obs value. The proposed model has a potential in predicting the removal rate of halogenated compounds by metallic iron under various conditions., (Copyright © 2017. Published by Elsevier Ltd.)

Haloacetaldehydes (HAs) are the third prevalent group of disinfection by-products (DBPs) of great health concern. In this study, their formation and speciation during chlorination were investigated for raw and process waters collected at three O3-biological activated carbon (BAC) advanced drinking water treatment plants. The results showed that all HA formation potentials (HAFPs) were highly enhanced whenever ozone was applied before or after conventional treatment. Sand filtration and BAC filtration could substantially reduce HAFPs. Trihalomethanes (THMs) were also measured to better understand the role of HAs in DBPs. Very different from HAFPs, THMFPs kept decreasing with the progress of treatment steps, which was mainly attributed to the different precursors for HAs and THMs. Brominated HAs were detected in bromide-containing waters. Chloral hydrate (CH) contributed from 25% to 48% to the total HAs formed in waters containing 100-150 μg L(-1) bromide, indicating the wide existence of other HAs after chlorination besides CH production. In addition, bromide incorporation factor (BIF) in HAs and THMs increased with the progress of treatment steps and the BIF values of THMs were generally higher than those of HAs. The BAC filtration following ozonation could significantly reduce HA precursors produced from ozonation but without complete removal. The brominated HAFPs in the outflow of BAC were still higher than their levels in the raw water. As a result, O3-BAC combined treatment was effective at controlling the total HAs, whereas it should be cautious for waters with high bromide levels., (Copyright © 2016 Elsevier Ltd. All rights reserved.)

The effects of calcium, cupric, ferrous and ferric ions on the formation of trihalomethanes (THMs) and haloacetic acids (HAAs) were investigated using natural organic matter (NOM), small molecular weight NOM surrogates and natural water samples. The results showed that the effects were greatly dependent on the disinfection byproduct (DBP) precursor structure and molecular weight, and metal ions species. While using NOM as precursors, addition of 4.00 mM calcium ions increased the formation of THMs, dihaloacetic acids (DHAAs) and trihaloacetic acids (THAAs) by 24-47%, 51-61% and 15-25%, respectively. Addition of cupric ions at 0.02 mM increased the formation of THMs and DHAAs by 74-83% and 90-100%, respectively, but decreased the formation of THAAs by 26-27%. Similar effect was not observed when 0.04 mM ferrous or ferric ions were added. The effects of calcium and cupric ions on DBP formation were generally more evident for the NOM surrogates than that for NOM. The primary catalytic effect of calcium ions was due to complexation and less sensitive to molecular structure or weight, while that of cupric ions was attributed to redox reactions and greatly dependent on molecular structure. Both ferric and ferrous iron had substantial effects on the DBP formation of surrogates (citric acid and catechol in particular), which implied that the catalytic effects of ferric and ferrous iron mainly depended on molecular weight. The catalytic effect of cupric ions was also observed on natural water samples, while the effects of calcium, ferrous and ferric ions on natural water samples were not evident., (Copyright © 2015 Elsevier Ltd. All rights reserved.)

The temperature of drinking water fluctuates naturally in water distribution systems as well as often deliberately heated for household or public uses. In this study, the temperature effect on the formation of disinfection by-products (DBPs) was investigated by monitoring the temporal variations of twenty-one DBPs during the chlorination of a humic precursors-containing water at different temperatures. It was found that chloroform, DCAA, TCAA, DCAN and CH were detected at the considerable level of tens of μg L(-1). The three regulated DBPs (chloroform, DCAA and TCAA) were found increasing with both contact time and water temperature, while the five typical emerging DBPs (DCAN, CH, TCNM 1,1-DCPN and 1,1,1-TCPN) revealed the significant auto-decomposition in addition to the initial growth in the first few hours. Increasing water temperature could enhance the formation rates of all the eight detected DBPs and the decomposition rates of the five emerging DBPs. Further, a kinetic model was developed for the simulation of DBP formation. The validity and universality of the model were verified by its excellent correlation with the detected values of each DBP species at various temperatures. The formation rates of 1,1-DCPN and 1,1,1-TCPN, and the decomposition rate of 1,1,1-TCPN were faster as compared to the other DBPs. And the formation reaction activation energies of CH, DCAN and 1,1-DCPN were relatively large, indicating that their occurrence levels in the finished water were more susceptible to temperature variations., (Copyright © 2012 Elsevier Ltd. All rights reserved.)

An innovative haloacetic acid (HAA) removal process was developed. The process consisted of a zero-valent iron (Fe(0)) column followed by a biologically active carbon (BAC) column that were efficient in degrading tri- and di-HAAs, and mono- and di-HAAs, respectively. The merit of the process was demonstrated by its performance in removing trichloroacetic acid (TCAA). An empty bed contact time of 10 min achieved nearly complete removal of 1.2 μM TCAA and its subsequent products, dichloroacetic acid (DCAA) and monochloroacetic acid (MCAA). HAA removal was a result of chemical dehalogenation and biodegradation rather than physical adsorption. Preliminary kinetic analyses were conducted and the pseudo-first-order rate constants were estimated at ambient conditions for Fe(0) reduction of TCAA and biodegradation of DCAA and MCAA by BAC. This innovative process is highly promising in removing HAAs from drinking water, swimming pool water, and domestic or industrial wastewater., (Copyright © 2012 Elsevier Ltd. All rights reserved.)