1. Cardiopulmonary benefits of respirator intervention against near road ambient particulate matters in healthy young adults: A randomized, blinded, crossover, multi-city study
- Author
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Wei Niu, Wanzhou Wang, Chen Huang, Zhihong Zhang, Le Ma, Rui Li, John Cherrie, Mark R. Miller, Miranda Loh, Jiahui Chen, Chun Lin, Shaowei Wu, Xinbiao Guo, and Furong Deng
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Air Pollutants ,China ,Ventilators, Mechanical ,Environmental Engineering ,Health, Toxicology and Mutagenesis ,Air pollution ,Public Health, Environmental and Occupational Health ,blood pressure ,Environmental Exposure ,General Medicine ,General Chemistry ,Pollution ,Lung function ,Young Adult ,Air Pollution ,Humans ,Environmental Chemistry ,Environmental Pollutants ,Particulate Matter ,Cities ,Respirator ,Particulate matter ,Heart rate variability - Abstract
Wearing a respirator is generally the most convenient individual intervention against ambient particulate matter (PM), and therefore there has been considerable research into its effectiveness. However, the effects of respirator intervention under different PM concentration settings have been insufficiently elucidated. We conducted a randomized, blinded, crossover intervention study in four representative cities in China in which 128 healthy university students spent 2 h walking along a busy road wearing either a real or a sham respirator and then spent the next 5 h indoors away from traffic pollution. Lung function, blood pressure, and heart rate variability were continuously measured throughout the visit. Linear mixed-effect models were fitted to evaluate the protective effects of respirator intervention on the cardiopulmonary indicators. Results showed that the beneficial effects of respirator intervention were only occasionally significant at specific time points or in specific cities or in selected parameters. Overall, respirator intervention was associated with reduced SBP (6.2 vs. 11.5 mmHg compared to baseline, p
- Published
- 2022
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