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Your search keyword '"Barbara J. Fueger"' showing total 2 results
Start Over Author "Barbara J. Fueger" Journal chemmedchem
2 results on '"Barbara J. Fueger"'

1. From In Situ to In Vivo: An In Situ Click-Chemistry-Derived Carbonic Anhydrase II Imaging Agent for Positron Emission Tomography

Author

Wolfgang Weber, Hartmuth C. Kolb, Helen Su, Barbara J. Fueger, Johannes Czernin, Vani P. Mocharla, Henry C. Padgett, and Joseph C. Walsh

Subjects
In situ, Fluorine Radioisotopes, Erythrocytes, Carbonic anhydrase II, Mice, SCID, Carbonic Anhydrase II, Biochemistry, Mice, In vivo, Drug Discovery, medicine, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, medicine.diagnostic_test, Chemistry, Organic Chemistry, Radiochemistry, Imaging agent, Positron emission tomography, Positron-Emission Tomography, Click chemistry, Molecular Medicine, Click Chemistry, Molecular imaging
Abstract

CA II makes a good PET: Discovering positron emission tomography (PET) probes with high target affinities is challenging. PET probe discovery using in situ click chemistry uses (19) F-bearing fragments as (18) F surrogates. This ensures that the lead hits and PET probes have equivalent chemical or biological characteristics, making PET probe discovery predictable and reliable.

Published
2012
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2. Inside Cover: From In Situ to In Vivo: An In Situ Click-Chemistry-Derived Carbonic Anhydrase II Imaging Agent for Positron Emission Tomography (ChemMedChem 1/2013)

Author

Joseph C. Walsh, Hartmuth C. Kolb, Johannes Czernin, Wolfgang Weber, Henry C. Padgett, Helen Su, Vani P. Mocharla, and Barbara J. Fueger

Subjects
Pharmacology, In situ, medicine.diagnostic_test, Chemistry, Carbonic anhydrase II, Organic Chemistry, Inorganic chemistry, Radiochemistry, Biochemistry, Imaging agent, In vivo, Positron emission tomography, Drug Discovery, Click chemistry, medicine, Molecular Medicine, Cover (algebra), General Pharmacology, Toxicology and Pharmaceutics, Molecular imaging
Published
2012
Full Text
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