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Your search keyword '"Stoykova, Boyka"' showing total 1 results
Start Over Author "Stoykova, Boyka" Topic 4-aminoantipyrine Journal chemistry. bulgarian journal of chemical education
1 results on '"Stoykova, Boyka"'

1. SONOCHEMICAL SYNTHESIS OF 4-AMINOANTIPYRINE SCHIFF BASES A ND EVALUATION OF THEIR ANTIMICROBIAL, ANTI-TYROSINASE AND DPPH SCAVENGING ACTIVITIES.

Author

Chochkova, Maya, Stoykova, Boyka, Romanova, Iva, Petrova, Petranka, Tsvetkova, Iva, Najdenski, Hristo, Nikolaeva-Glomb, Lubomira, Nikolova, Nadya, Ivanova, Galya, Chapkanov, Atanas, Milkova, Tsenka, Štícha, Martin, and Nemec, Ivan

Subjects
*CHEMICAL synthesis, *SCHIFF bases, *ANTI-infective agents, *PHENOL oxidase, *CHEMICAL scavengers
Abstract

A series of 4-(substituted benzylidene-amino)-2,3-dimethyl-1-phenyl- 3-pyrazoline-5-ones (3a-l) was obtained using sonochemical assisted reaction. The synthesized Schiff bases were evaluated for their antiviral, antibacterial, anticandida, DPPH scavenging and anti-tyrosinase activities in vitro. The antimicrobial screening results revealed that amongst the tested imines, compound 3l appeared to be а promising one (with a minimal inhibitory concentration 47 ug/ml). The most potent DPPH scavengers were azometines 3a and 3g. No significant inhibition on the monophenolase activity in vitro of mushroom tyrosinase was observed. [ABSTRACT FROM AUTHOR]

Published
2018

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