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Your search keyword '"Andrianov, A. A."' showing total 249 results
Start Over Author "Andrianov, A. A." Journal chemistry of heterocyclic compounds
249 results on '"Andrianov, A. A."'

27. Synthesis of novel [1-aziridinyl-(hydroxyimino)methyl]arenes and their cytotoxic activity

Author

A. Grigorjeva, Ivars Kalvinsh, V. Andrianov, Ilona Domracheva, Irina Shestakova, E. Yashchenko, and Aigars Jirgensons

Subjects
chemistry.chemical_compound, Cell culture, Chemistry, Stereochemistry, Organic Chemistry, Cytotoxic T cell, Aziridine, Oxime, IC50, In vitro
Abstract

The synthesis has been developed for novel potential anticancer agents whose structures contain an aziridine amidoxime group. The cytotoxic activity of all of the target compounds on different cell lines are given together with the in vitro IC50 and LD50 values found. The most promising anticancer agents were found to be the methyl 4-[1-aziridinyl(hydroxyimino)methyl]benzoate, 1-aziridinyl(2-naphthyl)-methanone oxime, and 1-aziridinyl(2-quinolyl)methanone oxime.

Published
2009

33. The chemistry of furazano-[3,4-b]pyrazine. 7. Properties of 5,6-diamino- and 5,6-dihydrazino-furazano[3,4-b]pyrazine

Author

I. B. Starchenkov, Victor Andrianov, and A. F. Mishnev

Subjects
chemistry.chemical_compound, Pyrazine, Chemistry, Organic Chemistry, Amine gas treating, Ring (chemistry), Furazan, Medicinal chemistry
Abstract

The reactions of 5,6-diamino- and 5,6-dihydrazinofurazano[3,4-b][yrazine that produce polycyclic or highly reactive compounds are reviewed. The furazan ring has a deactivating effect on the amine functions of these compounds.

Published
1999

34. Chemistry of furazano[3,4-b]pyrazine 6. 1,2,3-triazolo[4,5-b]furazano[3,4-b]pyrazines

Author

I. B. Starchenkov, Victor Andrianov, and A. F. Mishnev

Subjects
chemistry.chemical_compound, chemistry, Pyrazine, Stereochemistry, Organic Chemistry, Triazole, Aromaticity
Abstract

The reduction of 1,2,3-triazolo[4,5-e]furazano[3,4-b]pyrazine 6-oxide was investigated. By means of data from x-ray crystallographic analysis it was shown that there is a relation between the aromaticity and the structure of the obtained triazoles.

Published
1998

35. Chemistry of furazano[3,4-b]pyrazine. 5. 1,2,3-Triazolo[4,5-e]furazano[3,4-b]pyrazine 6-oxides

Author

Victor Andrianov, I. B. Starchenkov, and A. F. Mishnev

Subjects
chemistry.chemical_compound, Pyrazine, Chemistry, Organic Chemistry, Organic chemistry
Abstract

New representatives of a little-investigated class of compound-1,2,3-triazole 2-oxides — were obtained by a nonphotochemical method. Mononitroamines and dinitroamines are produced during their formation as intermediate products.

Published
1997

36. Chemistry of furazano[3,4-b]pyrazines

Author

I. B. Starchenkov and Victor Andrianov

Subjects
chemistry.chemical_compound, Pyrazine, Nucleophile, Chemistry, Organic Chemistry, Substitution (logic), Organic chemistry
Abstract

A method was developed for the synthesis of 5,6-dichlorofurazano[3,4-b]pyrazine (a compound with easily removed leaving groups). The optimum conditions for their substitution by various nucleophiles were determined.

Published
1997

37. Chemistry of furazano[3,4-b]pyrazines. 2. Nucleophilic substitution of the azido group in furazano[3,4-b]pyrazines

Author

A. F. Mishnev, I. B. Starchenkov, and Victor Andrianov

Subjects
chemistry.chemical_compound, Nucleophile, chemistry, Pyrazine, Group (periodic table), Stereochemistry, Organic Chemistry, Nucleophilic substitution, Tetrazole, Azide, Medicinal chemistry, Tautomer
Abstract

The corresponding 7-substituted furazano[3,4-b]tetrazolo[1,2-d]pyrazines were obtained by nucleophilic substitution of the azido group in 7-azidofurazano[3,4-b]tetrazolo[1,2-d]pyrazine. It was shown that these compounds exist in the tetrazole form in the crystalline state; in solutions, a tautomeric equilibrium is observed between the azide and tetrazole forms. Further reaction with nucleophiles leads to the production of 5,6-disubstituted furazano[3,4-b]pyrazines.

Published
1997

38. Synthesis and properties of derivatives of 4-aminofuroxan-3-carboxylic acid

Author

V. G. Andrianov

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Hydroxylamine, chemistry, Pyrimidine, Carboxylic acid, Organic Chemistry, Hydrazine, Polymer chemistry, Organic chemistry, Triethyl orthoformate, Ring (chemistry)
Abstract

4-Amino-3-cyanofuroxan, obtained by the oxidation of aminocyanoglyoxime, reacts with hydrazine and hydroxylamine to form the amidrazone and amidoxime respectively of 4-aminofuroxan-3-carboxylic acid. The reaction of the amidoxime with triethyl orthoformate can lead to closure of both the pyrimidine and the 1,2,4-oxadiazole ring.

Published
1997

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