1. New (9betaH)-lanostanes and lanostanes from Mikania aff. jeffreyi (Asteraceae).
- Author
-
Mendes CC, Sandes LQ, Cruz FG, and Roque NF
- Subjects
- Magnetic Resonance Spectroscopy, Molecular Conformation, Stereoisomerism, Triterpenes isolation & purification, Mikania chemistry, Triterpenes chemistry
- Abstract
Four new (9betaH)-lanostanes, i.e., (9betaH)-3beta-acetoxylanosta-7,24-diene, (9betaH)-3-oxolanosta-7,24-diene, (9betaH,24R)-3beta-acetoxy-24-hydroxylanosta-7,25-diene, and (9betaH,24S)-3beta-acetoxy-24-hydroxylanosta-7,25-diene, two new lanostanes, i.e., (24R)-3beta-acetoxy-24-hydroxylanosta-8,25-diene and (24S)-3beta-acetoxy-24-hydroxylanosta-8,25-diene, and two known lanostanes, i.e., 3beta-acetoxylanosta-8,24-diene and 3-oxolanosta-8,24-diene, were obtained from a new Mikania species (Asteraceae) besides pentacyclic triterpenes, steroids, and diterpenes. The structures of the compounds were determined by spectroscopic methods. This is the second study about acetyl-lanosterols from higher plants. Moreover, (9betaH)-lanostanes are very rare metabolites from dicotyledone angiosperms. The occurrence of these terpenes together in the same plant makes the species a good source for lanostane- and (9betaH)-lanostane-biosynthesis studies.
- Published
- 2009
- Full Text
- View/download PDF