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Your search keyword '"Ji-Hee Han"' showing total 3 results
Start Over Author "Ji-Hee Han" Journal chemistry - a european journal
3 results on '"Ji-Hee Han"'

1. Simultaneous Imaging of Mitochondria and Lysosomes by Using Two-Photon Fluorescent Probes

Author

Min Kyu Park, Ji Hee Han, Sun Keun Park, Bong Rae Cho, Hwan Myung Kim, Chang Su Lim, and Hyung Joong Kim

Subjects
Diagnostic Imaging, Photons, Photon, Molecular Structure, Chemistry, Organic Chemistry, General Chemistry, Mitochondrion, Fluorescence, Catalysis, Mitochondria, Mice, Autofluorescence, Two-photon excitation microscopy, Biophysics, Animals, Lysosomes, Fluorescent Dyes
Published
2012
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2. A Small-Molecule Two-Photon Probe for Nitric Oxide in Living Tissues

Author

Hwan Myung Kim, Eun Won Seo, Cheol Ho Heo, Ji Hee Han, Bong Rae Cho, and Jae Ho Shin

Subjects
Diagnostic Imaging, Photons, Molecular Structure, Organic Chemistry, Analytical chemistry, General Chemistry, Nitric Oxide, Small molecule, Fluorescence, Catalysis, Nitric oxide, Mice, chemistry.chemical_compound, Microscopy, Fluorescence, Multiphoton, chemistry, Two-photon excitation microscopy, Microscopy, Biophysics, Animals, Molecular imaging, Nitrogen oxides, Fluorescent Dyes
Abstract

Two-photon microscopy (TPM) has become an indispensable tool in the study of biology and medicine due to the capability of this method for molecular imaging deep inside intact tissues. For the maximum utilization of TPM, a variety of two-photon (TP) probes for specific applications are needed. In this article, we report a small-molecule TP probe (ANO1) for nitric oxide (NO) that shows a rapid and specific NO response, a 68-fold fluorescence enhancement in response to NO, and a maximum TP-action cross-section of 170 GM (GM: 10(-50) cm(4) photon(-1)) upon reaction with excess NO. This probe can be easily loaded into cells and tissues and can real-time monitor NO in living tissues at 100-180 μm depth for longer than 1200 s through the use of TPM, with minimum interference from other biologically relevant species.

Published
2012
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