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Various silyl enol ethers gave the corresponding mono benzyl products in moderate to good yields by the reaction with benzyl bromide in the presence of silver perchlorate in dichloromethane at −78–...

Swainsonine, a potential immunoregulator, was synthesized from D-mannose via an intermediate, methyl 4,8-imino-2,3-O-isopropylidene-4,6,7,8-tetradeoxy-α-D-manno-octopyranoside.

Various 5-trimethylsiloxyoxazoles were synthesized by the silylation of 2-oxazolin-5-ones using chlorotrimethylsilane and triethylamine in high yields. Diels–Alder reaction of the siloxyoxazoles with N-phenylmaleinimide or dimethyl maleate afforded the corresponding substituted pyridines in high yields. This method was applied to the synthesis of Vitamin B6 derivatives starting from N-formylalanine.

3,7-Dihydroxy- and 3-substituted 7-hydroxypyrazolo[4,3-d]pyrimidines were synthesized from diethyl oxaloacetate and ethyl acylpyruvates via ethyl 4-amino-5-oxo-2-pyrazoline-3-carboxylate hydrochloride and ethyl 5-substituted 4-amino-3-pyrazolecarboxylates, respectively.

Two stereoisomers of swainsonine, (1S,2S,8S,8aR)-1,2,8-trihydroxyoctahydroindolizine and the corresponding (1S,2R,8S,8aR) derivative, were synthesized from D-glucose via one step cyclization to the 5-oxo-1,2,8-trihydroxyoctahydroindolizine derivative.