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Start Over Author "Gary Lim" Journal chemischer informationsdienst
4 results on '"Gary Lim"'

1. ChemInform Abstract: NUCLEAR ANALOGS OF β-LACTAM ANTIBIOTICS. XIII. STRUCTURE ACTIVITY RELATIONSHIPS IN THE ISOCEPHALOSPORIN SERIES

Author

Donald E. Horning, Terry T. Conway, Terrence W. Doyle, Marcel Menard, Leeson R. Morris, Alain Martel, Gary Lim, James L. Douglas, Martin Misiek, Bing Yu Luh, C. F. Ferrari, and Bernard Belleau

Subjects
Quantitative Biology::Biomolecules, chemistry.chemical_compound, Series (mathematics), Stereochemistry, medicine.drug_class, Chemistry, Cephalosporin, Antibiotics, medicine, Lactam, General Medicine, Nuclear Experiment
Abstract

The general synthetic scheme to nuclear analogs of cephalosporins described in previous papers of this series is reviewed and the synthesis of a series of sidechain derivatives is given. Thus, syst...

Published
1981
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2. ChemInform Abstract: NUCLEAR ANALOGS OF β-LACTAM ANTIBIOTICS. II. SYNTHESIS OF O-2-ISOCEPHEMS

Author

Bernard Belleau, Gary Lim, Lee Morris, Terry T. Conway, James L. Douglas, Marcel Menard, Michael Casey, Bing Yu Luh, Terrence W. Doyle, Pierre Rivest, and Daniel Tim-Wu Chu

Subjects
Chemistry, medicine.drug_class, Mesylate, Acetal, Antibiotics, Total synthesis, Alcohol, General Medicine, Enol, chemistry.chemical_compound, Hydrolysis, medicine, Lactam, Organic chemistry
Abstract

The preparation by total synthesis of a new class of β-lactam antibiotics is reported. Conversion of alcohol 1b to its mesylate 9b followed by hydrolysis of the acetal to the enol 1b and base-catal...

Published
1977
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