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Start Over Author "Chiu Ming Chen" Journal chemischer informationsdienst
2 results on '"Chiu Ming Chen"'

1. ChemInform Abstract: THE REACTION OF INDOLE WITH PROPIOLIC ACID

Author

Chiu-Ming Chen and Sheng‐Hsu Zee

Subjects
chemistry.chemical_classification, Indole test, Hydrolysis, chemistry.chemical_compound, Mole ratio, Propiolic acid, chemistry, Decarboxylation, Carboxylic acid, Yield (chemistry), General Medicine, Medicinal chemistry, Adduct
Abstract

The reaction of indole with propiolic acid ia 1 : 1 mole ratio gave an adduct (I) of 2 : 1 addition with decarboxylation. The reaction of indole with propiolic acid methyl ester gave a 2 : 1 adduct (II). Hydrolysis of adduct II yield the corresponding carboxylic acid (IV). Decarboxylation of IV also gave I. The mechanism of title reaction were fully studied.

Published
1975
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