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Your search keyword '"Timothy J. Miles"' showing total 4 results
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4 results on '"Timothy J. Miles"'

1. ChemInform Abstract: The Design of Efficient and Selective Routes to Pyridyl Analogues of 3-Oxo-3,4-dihydro-2H-1,4-(benzothiazine or benzoxazine)-6-carbaldehydes

Author

Gerald Brooks, Neil D. Pearson, Timothy J. Miles, Alan Joseph Hennessy, Tony W. Peng, Nathan A. Owston, Graham Elgin Jones, Roger Edward Markwell, Steven Dabbs, and David T. Davies

Subjects
chemistry.chemical_compound, Chemistry, General Medicine, Benzothiazine, Combinatorial chemistry, Connection (mathematics)
Abstract

In connection with a programme concerning the antibacterial medicinal chemistry, different routes are presented for the synthesis of aldehydes (V), (VIII), (XI), and (XV) which allow the preparation of multi-gram quantities.

Published
2010

2. ChemInform Abstract: The Design of Efficient and Selective Routes to Pyridyl Analogues of 2,3-Dihydro-1,4-benzodioxin-6-carbaldehyde

Author

David T. Davies, Alan Joseph Hennessy, Timothy J. Miles, Pamela Brown, Neil D. Pearson, Christopher Barfoot, and Steven Dabbs

Subjects
chemistry.chemical_compound, chemistry, organic chemicals, heterocyclic compounds, General Medicine, Kojic acid, Combinatorial chemistry
Abstract

Six routes starting from commercially available kojic acid allow the preparation of pyridyl aldehydes (I)-(VI), which may be of interest as antibacterial drugs.

Published
2010

3. ChemInform Abstract: Intramolecular Diels-Alder Reactions of α,β-Unsaturated Oxime Ethers as 1-Azadienes: Synthesis of [c]-Fused Pyridines

Author

Timothy E. Hurst, Timothy J. Miles, and Christopher J. Moody

Subjects
chemistry.chemical_compound, Diene, chemistry, Salicylaldehyde, Intramolecular force, Diels alder, Organic chemistry, General Medicine, Oxime
Abstract

The intramolecular hetero-Diels–Alder reaction of α,β-unsaturated oxime ethers as the diene with acetylenic dienophiles, readily prepared from salicylaldehyde derivatives, is described as a rapid and versatile route to [c]-annelated pyridines in modest to good yields.

Published
2008

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