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Your search keyword '"Sergio G. Duron"' showing total 2 results
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2 results on '"Sergio G. Duron"'

1. ChemInform Abstract: Annulation of Thioimidates and Vinyl Carbodiimides to Prepare 2-Aminopyrimidines, Competent Nucleophiles for Intramolecular Alkyne Hydroamination. Synthesis of (-)-Crambidine

Author

Sergio G. Duron, David Y. Gin, Nicholas R. Perl, Sudeep Prajapati, Nathan D. Ide, and Hahdi H. Perfect

Subjects
chemistry.chemical_classification, Annulation, Nucleophile, Chemistry, Intramolecular force, Convergent synthesis, Alkyne, General Medicine, Hydroamination, Combinatorial chemistry, Crambidine
Abstract

A convergent synthesis of (−)-crambidine is reported. The sequence capitalizes on two novel key transformations, including a [4+2] annulation of thioimidates with vinyl carbodiimides and an alkyne hydroamination employing 2-aminopyrimidine nucleophiles.

Published
2010
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2. ChemInform Abstract: Synthesis and Determination of Absolute Configuration of the Bicyclic Guanidine Core of Batzelladine A

Author

David Y. Gin and Sergio G. Duron

Subjects
chemistry.chemical_compound, Natural product, chemistry, Bicyclic molecule, Stereochemistry, Absolute configuration, General Medicine, Guanidine, Ring (chemistry)
Abstract

[reaction: see text] The synthesis of a selectively protected form of the bicyclic guanidine fragment of batzelladine A from L-aspartic acid is reported, thereby establishing the absolute configuration of the bicyclic guanidine ring system within the natural product.

Published
2010
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