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1. ChemInform Abstract: anti-Diastereoselective Synthesis of CF3-Containing Spirooxazolines and Spirooxazines via Regiospecific Trifluoromethylative Spirocyclization by Photoredox Catalysis

Author

Munetaka Akita, Takashi Koike, Naoki Noto, and Kazuki Miyazawa

Subjects
Cyclic Alkenes, chemistry.chemical_compound, chemistry, Amide, Photoredox catalysis, General Medicine, Combinatorial chemistry
Abstract

Starting from cyclic alkenes bearing an amide tether the title reaction provides trifluoromethylated spirooxazolines or spirooxazines in moderate to high yields and with moderate to high anti-diastereoselectivity.

Published
2015

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