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Your search keyword '"Kishore, V."' showing total 27 results
Start Over Author "Kishore, V." Journal cheminform
27 results on '"Kishore, V."'

1. ChemInform Abstract: A Direct Access to Bioactive Fused N-Heterocyclic Acetic Acid Derivatives

Author

Dipali Ahuja, Kishore V. L. Parsa, Manojit Pal, Ravikumar Kapavarapu, B. Ramudu, Raju Adepu, A. Rajitha, and Atul Kumar Sharma

Subjects
Acetic acid, chemistry.chemical_compound, chemistry, Cascade reaction, Ligand, Rapid access, General Medicine, Combinatorial chemistry
Abstract

A rapid access to novel, fused N-heterocyclic acetic acid derivatives via a ligand- and additive-free Cu-mediated domino reaction of amides (I) with nitriles (II) is developed.

Published
2014
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2. ChemInform Abstract: Synthesis of 2H-1,3-Benzoxazin-4(3H)-one Derivatives Containing Indole Moiety: Their in vitro Evaluation Against PDE4B

Author

Chekuri Sharmila Rani, Manojit Pal, Bethala Jawahar Luther, Raja Mohan Rao, Namburi Suresh, Ravikumar Kapavarapu, Kishore V. L. Parsa, and Mandava V. Rao

Subjects
Indole test, PDE4B, Phosphodiesterase-4, Stereochemistry, Chemistry, Organic chemistry, Moiety, General Medicine, In vitro
Abstract

10 Title compounds of type (III) are prepared and tested as inhibitors of phosphodiesterase 4 (PDE4).

Published
2014
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3. ChemInform Abstract: Montmorillonite K-10 Catalyzed Green Synthesis of 2,6-Unsubstituted Dihydropyridines as Potential Inhibitors of PDE4

Author

L. Srinivasula Reddy, Y. Lingappa, G. Rajeshwar Reddy, Manojit Pal, T. Ram Reddy, Kishore V. L. Parsa, K. Shiva Kumar, and Chandana Lakshmi T. Meda

Subjects
Green chemistry, chemistry.chemical_compound, Montmorillonite K-10, Montmorillonite, chemistry, Organic chemistry, General Medicine, Catalysis
Abstract

A variety of 2,6-disubstituted dihydropyridines (IV) (15 examples) is obtained in a multicomponent reaction of anilines, aldehydes and 3,3-diethoxypropionate (I) using montmorillonite K10 as cheap and reusable catalyst.

Published
2013
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4. ChemInform Abstract: Facile Assembly of Two 6-Membered Fused N-Heterocyclic Rings: A Rapid Access to Novel Small Molecules via Cu-Mediated Reaction

Author

Kishore V. L. Parsa, Manojit Pal, Raju Adepu, Girdhar Singh Deora, Rajnikanth Sunke, C. Malla Reddy, G. Rama Krishna, D. Rambabu, and Chandana Lakshmi T. Meda

Subjects
biology, Cascade reaction, Chemistry, Rapid access, Tetra, General Medicine, biology.organism_classification, Combinatorial chemistry, Small molecule
Abstract

With a view to find novel inhibitors of phosphodiesterase-4, a variety of fused tetra- and pentacyclic heterocycles is prepared by Cu-mediated domino reaction of starting carboxylic esters with nitriles (36 examples).

Published
2013
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5. ChemInform Abstract: Pyrrolo[2,3-b]quinoxalines as Inhibitors of Firefly Luciferase: Their Cu-Mediated Synthesis and Evaluation as False Positives in a Reporter Gene Assay

Author

Ravada Kishore, Manojit Pal, Chandana Lakshmi T. Meda, Girdhar Singh Deora, Md. Shafiqur Rahman, Ali Nakhi, and Kishore V. L. Parsa

Subjects
Reporter gene, Chemistry, False positive paradox, Luciferase, General Medicine, Molecular biology
Abstract

2-Substituted pyrrolo[2,3-b]quinoxalines (V) are prepared in a single reaction from 3-alkynyl-2-chloroquinoxalines (III) using methanesulfonamide as ammonia surrogate.

Published
2013
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6. ChemInform Abstract: A New Cascade Reaction: Concurrent Construction of Six and Five Membered Rings Leading to Novel Fused Quinazolinones

Author

V. Sreenivasa Rao, Chandana Lakshmi T. Meda, Ravikumar Kapavarapu, Ahamed A. Jafar, Manojit Pal, Kishore V. L. Parsa, P. Mahesh Kumar, and K. Siva Kumar

Subjects
Inhibitory potential, Phosphodiesterase-4, Cascade reaction, Chemistry, Stereochemistry, General Medicine, In vitro
Abstract

The compounds (IV) are evaluated in vitro for their inhibitory potential against phosphodiesterase 4.

Published
2012
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7. ChemInform Abstract: Design and Synthesis of 4-Alkynyl Pyrazoles as Inhibitors of PDE4: A Practical Access via Pd/C-Cu Catalysis

Author

Chandana Lakshmi T. Meda, Kishore V. L. Parsa, Manojit Pal, Ajit Kandale, Dhilli Rao Gorja, Khagga Mukkanti, and K. Shiva Kumar

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Chemistry, Iodide, macromolecular substances, General Medicine, Pyrazole, Combinatorial chemistry, Catalysis
Abstract

A facile Pd—C/CuI/PPh3 mediated C—C bond forming reaction between pyrazole iodide and several terminal alkynes leads to title compounds (III).

Published
2012
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8. ChemInform Abstract: Montmorillonite K-10 Mediated Green Synthesis of Cyano Pyridines: Their Evaluation as Potential Inhibitors of PDE4

Author

Kishore V. L. Parsa, Subbarao Jammula, L. Srinivasula Reddy, G. Rajeshwar Reddy, Manojit Pal, T. Ram Reddy, Chandana Lakshmi T. Meda, Ravikumar Kapavarapu, and Y. Lingappa

Subjects
Green chemistry, chemistry.chemical_compound, Montmorillonite K-10, Montmorillonite, chemistry, Organic chemistry, Regioselectivity, Alcohol, General Medicine, Catalysis, Malononitrile
Abstract

Functionalized cyanopyridines (V) (18 examples) are efficiently obtained in a chemo- and regioselective four-component reaction of β-keto ester, arylaldehyde, malononitrile, and an alcohol using montmorillonite K10 as efficient and reusable catalyst.

Published
2012
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9. ChemInform Abstract: AlCl3-Induced C-Arylation/Cyclization in a Single Pot: A New Route to Benzofuran- Fused N-Heterocycles of Pharmacological Interest

Author

C. Malla Reddy, K. Krishna Priya, Kishore V. L. Parsa, D. Rambabu, K. Shiva Kumar, G. Rama Krishna, Raju Adepu, Ravikumar Kapavarapu, and Manojit Pal

Subjects
chemistry.chemical_compound, chemistry, Furan, Organic chemistry, General Medicine, Resorcinol, Benzofuran
Abstract

The AlCl3-mediated cyclocondensation of 2,3-dichloropyrazine derivatives with 2-naphthol or resorcinol monoalkyl ethers offers a direct synthesis of various polycyclic bis-fused furan derivatives.

Published
2012
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10. ChemInform Abstract: Construction of a Six-Membered Fused N-Heterocyclic Ring via a New 3-Component Reaction: Synthesis of (Pyrazolo)pyrimidines/pyridines

Author

Manojit Pal, Ravikumar Kapavarapu, P. Mahesh Kumar, Khagga Mukkanti, Pradeep K. Mohakhud, Kishore V. L. Parsa, and K. Siva Kumar

Subjects
chemistry.chemical_compound, Acetic acid, chemistry, Component (thermodynamics), chemistry.chemical_element, General Medicine, Ring (chemistry), Triflic acid, Medicinal chemistry, Oxygen, Catalysis
Abstract

A conceptually new three-component reaction was developed to construct a six-membered fused N-heterocyclic ring affording (pyrazolo)pyrimidines/pyridines as potential inhibitors of PDE4. The reaction is catalyzed by triflic acid in acetic acid in the presence of aerial oxygen.

Published
2012
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11. ChemInform Abstract: Novel 1-Alkynyl Substituted 1,2-Dihydroquinoline Derivatives from Nimesulide (and Their 2-Oxo Analogues): A New Strategy to Identify Inhibitors of PDE4B

Author

Ravikumar Kapavarapu, Khagga Mukkanti, Chandana Lakshmi T. Meda, Kishore V. L. Parsa, Suresh Babu Nallapati, Shylaprasad Durgadas, Sarbani Pal, and Manojit Pal

Subjects
PDE4B, Chemistry, Stereochemistry, medicine, General Medicine, Nimesulide, medicine.drug
Abstract

A number of novel arylpropynyl-substituted dihydroquinoline derivatives related to nimesulide [cf.

Published
2012
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25. ChemInform Abstract: Total Synthesis of Didemnins, A, B,and C.

Author

RINEHART, K. L. JUN., primary, KISHORE, V., additional, NAGARAJAN, S., additional, LAKE, R. J., additional, GLOER, J. B., additional, BOZICH, F. A., additional, LI, K.-M., additional, MALECZKA, R. E. JUN., additional, TODSEN, W. L., additional, MUNRO, M. H. G., additional, SULLINS, D. W., additional, and SAKAI, R., additional

Published
1988
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