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From the stems of Kadsura heteroclita (Roxb.) Craib, a new novel C19 homolignan, heteroclitin N (1), as well as three new lignans, heteroclitins OQ (2–4), were isolated. Their structures were elucidated based on spectral analysis, including 1D and 2D NMR experiments. There is an additional spirocyclic oxirane system in heteroclitin O (2), which is the first example of a lignan with an oxirane ring in a spirobenzofuranoid dibenzocyclooctene structure in the genus Kadsura.

Two new dibenzocyclooctane lignans, kadsurindutins A (1) and B (2), were isolated from the stems of Kadsura induta, together with the known, structurally related lignans schisantherin L (3), schisantherin P (4), kadsulignan L (5), and neokadsuranin (6). Their structures and configurations were elucidated by spectroscopic methods (UV, ORD, CD, IR, 1D- and 2D-NMR) in combination with mass-spectrometric (HR-MS) techniques. Compounds 1, 5, and 6 showed in vitro antiviral effects on hepatitis B virus.

Four new lignans, heteroclitins I-L (1-4), were isolated from the stems of Kadsura heteroclita (Roxb.) Craib. Their chemical structures were elucidated on the basis of ID and 2D NMR.

Three new dibenzocyclooctane-type lignans, kadsutherins A–C (1–3), were isolated from the stems of two Kadsura species. Their structures and configurations were elucidated by spectroscopic methods including 2D-NMR and HR-MS techniques. Kadsutherin C (3) is the first dibenzocyclooctane lignan without an oxygen-containing substituent at C(2).