Search

Your search keyword '"Gary S. Nichol"' showing total 8 results
Start Over Author "Gary S. Nichol" Journal cheminform
8 results on '"Gary S. Nichol"'

1. ChemInform Abstract: Amine-Activated Iron Catalysis: Air- and Moisture-Stable Alkene and Alkyne Hydrofunctionalization

Author

Neil Brian Carter, Amy J. Challinor, Gary S. Nichol, Stephen P. Thomas, and Marc Calin

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Moisture, Alkene, Hydrosilylation, Alkyne, Organic chemistry, Amine gas treating, General Medicine, Catalysis
Abstract

An operationally simple hydrosilylation of alkenes is developed using a stable Fe(II)-precatalyst with in situ activation by iPr2NEt.

Published
2016

2. ChemInform Abstract: Enantioselective Nickel-Catalyzed Hydrocyanation Using Chiral Phosphine-Phosphite Ligands: Recent Improvements and Insights

Author

Gary S. Nichol, Hans-Günther Schmalz, Anna Falk, Alberto Cavalieri, and Dieter Vogt

Subjects
Nickel, chemistry.chemical_compound, chemistry, Hydrocyanation, Enantioselective synthesis, chemistry.chemical_element, General Medicine, Combinatorial chemistry, Phosphine, Catalysis
Abstract

This method allows Markovnikov-like addition of HCN to vinylarenes in good to high yields and with excellent enantioselectivities.

Published
2016

4. ChemInform Abstract: Facile, Novel Two-Step Syntheses of Benzimidazoles, Bis-benzimidazoles, and Bis-benzimidazole-dihydroquinoxalines

Author

Gary S. Nichol, Zhigang Xu, Alexandra P. Cappelli, Christopher Hulme, Justin Dietrich, and Arthur Y. Shaw

Subjects
Benzimidazole, chemistry.chemical_compound, chemistry, Two step, Condensation, General Medicine, Combinatorial chemistry
Abstract

A series of title compounds is synthesized by a strategy which involves Ugi four-component condensation of the isonitrile (I) followed by TFA-mediated deprotection and cyclization.

Published
2012

5. ChemInform Abstract: Thio-Claisen Rearrangement Used in Preparing anti-β-Functionalized γ,δ-Unsaturated Amino Acids: Scope and Limitations

Author

Gary S. Nichol, Kwang Soo Lee, Sukeshi J. Mehta, Hongchang Qu, Xuyuan Gu, Bryan Grossman, Zhihua Liu, and Victor J. Hruby

Subjects
Claisen rearrangement, chemistry.chemical_classification, Scope (project management), Chemistry, Stereochemistry, Enantioselective synthesis, Thio, General Medicine, Combinatorial chemistry, Amino acid
Abstract

FeBr3-catalyzed or LDA-mediated S-alkylation of thioamides followed by thio-Claisen rearrangement allows a regio-, diastereo-, and enantioselective access to the title compounds.

Published
2012

8. ChemInform Abstract: Efficient Organocatalytic α-Sulfenylation of Substituted Piperazine-2,5-diones

Author

Ramin Dubey, Gary S. Nichol, Bogdan Olenyuk, and Nathan W. Polaske

Subjects
Piperazine, chemistry.chemical_compound, chemistry, Reagent, Electrophile, Triazole, chemistry.chemical_element, Organic chemistry, General Medicine, Lewis acids and bases, Cinchona Alkaloids, Sulfur, Catalysis
Abstract

Organocatalytic alpha-sulfenylation of substituted piperazine-2,5-diones is reported through the use of cinchona alkaloids as Lewis bases and electrophilic sulfur transfer reagents. 1-Phenylsulfanyl[1,2,4]triazole, a novel sulfur transfer reagent, gave excellent product yields with a number of substituted piperazine-2,5-diones under mild conditions. Catalyst loading, stoichiometry of sulfur electrophile, temperature and solvent were optimized to achieve high product yields.

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results