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1. ChemInform Abstract: Highly Efficient Oxidative Dimerization of Thioamides to 3,5-Disubstituted 1,2,4-Thiadiazoles Mediated by DDQ

Author

Dong-Ping Cheng, Jizhong Yan, Wen Zheng, and Ruiwen Luo

Subjects
Thiadiazoles, Chemistry, General Medicine, Oxidative phosphorylation, Combinatorial chemistry
Abstract

A highly efficient oxidative dimerization of thioamides by 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) is reported. The reaction is carried out in ClCH2CH2Cl at room temperature. The corresponding 3,5-disubstituted 1,2,4-thiadiazoles are obtained in good to excellent yields.

Published
2012

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