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Your search keyword '"A. I. Kleimenov"' showing total 1 results
Start Over Author "A. I. Kleimenov" Journal cheminform
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1. ChemInform Abstract: Reaction of 1-Substituted Tetrahydro-β-carbolines with Activated Alkynes — A New Original Approach to the Synthesis of Tetrahydroazocino[5,4-b]indoles

Author

E. G. Dolgova, Tatiana N. Borisova, A. I. Kleimenov, Elena A. Sorokina, Larisa N. Kulikova, Leonid G. Voskressensky, Alexey V. Varlamov, and Alexander A. Titov

Subjects
Dimethyl acetylenedicarboxylate, Ethyl propiolate, chemistry.chemical_compound, Ethanol, chemistry, General Medicine, Methanol, Acetonitrile, Medicinal chemistry
Abstract

The transformations of 1-substituted tetrahydro-β-carbolines by the action of activated alkynes were studied. The action of dimethyl acetylenedicarboxylate in methanol gives products of the opening of the tetrahydropyridine fragment, namely, 2-methoxyalkylindoles. The action of ethyl propiolate in ethanol and of tosylacetylene in methanol gives mixtures of azocino[5,4-b]indoles and 2-alkoxyindoles. The action of ethyl propiolate in acetonitrile gives azocinoindoles.

Published
2008

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