1. Recyclable polymeric pi-acid catalyst effective on Mannich-type reaction in water
- Author
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Hiroshi Furukawa, Yukio Masaki, Kouichi Yamazaki, Akichika Itoh, Tomoyasu Yamada, Yoshitsugu Arai, and Hyouei Kawai
- Subjects
Polymers ,Chemistry, Organic ,Methacrylate ,Catalysis ,Styrene ,Mannich Bases ,chemistry.chemical_compound ,Acetals ,Isobutyrates ,Drug Discovery ,Nitriles ,Copolymer ,Organic chemistry ,Amines ,chemistry.chemical_classification ,Aldehydes ,Acetal ,Water ,General Chemistry ,General Medicine ,Polymer ,Organic Chemistry Phenomena ,Solvent ,Butyrates ,chemistry ,Models, Chemical ,Methacrylates ,Ethyleneglycol dimethacrylate - Abstract
Polymer-supported dicyanoketene acetal (poly-DCKA-1), synthesized by copolymerization of a DCKA bearing a 4-vinylbenzyl group with ethyleneglycol dimethacrylate, was found to be an excellent recyclable catalyst for the three-component Mannich-type reaction of aldehydes, aromatic amines, and TMS enolate of ethyl isobutyrate in water as the sole solvent.
- Published
- 2006