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Enantiomerically enriched five‐ and six‐membered benzo oxygen heterocycles are privileged architectures in functional organic molecules. Over the last several years, many effective methods have been established to access these compounds. However, comprehensive documents cover updated methodologies still in highly demand. In this review, recent transition metal catalyzed transformations lead to chiral five‐ and six‐membered benzo oxygen heterocycles are presented. The mechanism and chirality transfer or control processes are also discussed in details. [ABSTRACT FROM AUTHOR]

In recent years, sulfenate anions as key intermediates in enantioselective synthesis have attracted considerable attention. Typically, development of novel synthetic methods to generate sulfenate anions allows for the preparation of various enantiopure sulfoxides, which are prevalently used as auxiliaries, ligands, organocatalysts, and biologically active compounds. This review presents the in situ preparation methods and the recent applications of sulfenate anions in catalytic asymmetric synthesis of chiral sulfoxides. [ABSTRACT FROM AUTHOR]

Chiral sulfones extensively exist in drugs, agricultural chemicals, chiral organic intermediates, and functional materials. Their importance causes the rapid development of their synthetic methods in recent years. Many transition metal complex catalysts with chiral ligands and chiral organocatalysts are adopted in synthesis of chiral sulfones. Most of the methods to construct chiral sulfones are based on the reduction of unsaturated sulfones and the introduction of sulfone groups into unsaturated hydrocarbons. This review describes all classes of asymmetric reactions for synthesis of chiral sulfones. [ABSTRACT FROM AUTHOR]

In recent years, multicomponent reactions with inorganic and organic sulfur compounds as one of reactants have achieved a remarkable development. In this review, we summarize recent advances in the multicomponent reactions involving sulfur components, which include elemental sulfur, sodium metabisulfite, sodium hyposulfite, potassium pyrosulfite, DABSO, sodium sulfide, thiocyanate, sulfur dioxide, carbon disulfide and other divalent, tetravalent and hexavalent organosulfur compounds. [ABSTRACT FROM AUTHOR]

Sulfoximines are widely used as medicines, agricultural chemicals, chiral precursors, and chiral ligands in asymmetric synthesis, as well as pivotal intermediates for the construction of heterocyclic compounds. NH‐sulfoximines may be synthesized from thioethers, sulfoxides, sulfilimines, and sulfinamides. NH‐sulfoximines can undergo various transformations, such as arylations, alkylations, vinylations, and alkynylations. Here, we review the methods that have been applied to the syntheses and transformations of NH‐sulfoximines. [ABSTRACT FROM AUTHOR]

Chiral thioethers is an important class of organosulfur molecules with extensive applications, especially in the field of medicine and organic synthesis. This review discusses the recent progress of synthesis of enantioenriched chiral thioethers and hopes to be helpful for related research in the future. It is summarized from organosulfur compounds‐participating organic reaction types, including nucleophilic substitution, cross coupling, sulfa‐Michael addition, sulfenylation, asymmetric allylic reaction, asymmetric Doyle‐Kirmse reaction, Pummerer‐type rearrangement, Smiles rearrangement,[2,3] Stevens and Sommelet‐Hauser rearrangement. [ABSTRACT FROM AUTHOR]

Abstract: Most of compounds containing more than one reactive groups may produce several byproducts during the coupling process. Selective carbon‐heteroatom coupling reactions, which have merits of high synthetic efficiency and step economy, are the best choice to resolve the problem. Although they have made great progress, they deserve further exploration. This review discusses their recent advances and intend to inspire the research in the future. It is organized on the basis of selective carbon‐heteroatom coupling reaction types, including selective C−N and C−N, C−N and C−O, C−O and C−O, C−C and C−N coupling reactions. [ABSTRACT FROM AUTHOR]