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Your search keyword '"Floxuridine metabolism"' showing total 6 results
Start Over Descriptor "Floxuridine metabolism" Journal chemical pharmaceutical bulletin
6 results on '"Floxuridine metabolism"'

1. Enzymatic cleavage of various fluorinated pyrimidine nucleosides to 5-fluorouracil and their antiproliferative activities in human and murine tumor cells.

Author

Miwa M, Cook A, and Ishitsuka H

Subjects
Animals, Cell Division drug effects, Floxuridine pharmacology, Fluorouracil pharmacology, Humans, Mice, Mice, Inbred Strains, Neoplasms, Experimental enzymology, Neoplasms, Experimental pathology, Substrate Specificity, Thymidine Phosphorylase metabolism, Uridine Phosphorylase metabolism, Floxuridine metabolism, Fluorouracil metabolism
Published
1986
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4. Specificity of esterases and structures of prodrug esters. III. Activity of rat tissue homogenates, rat plasma and porcine liver esterase for the hydrolysis of 3',5'-bis-dicarboxylic acid hemiesters of 5-fluoro-2'-deoxyuridine.

Author

Kawaguchi T, Suzuki Y, Nambu N, and Nagai T

Subjects
Animals, Dicarboxylic Acids metabolism, Esters metabolism, Floxuridine metabolism, Hydrolysis, In Vitro Techniques, Rats, Substrate Specificity, Swine, Esterases metabolism, Floxuridine analogs & derivatives, Liver enzymology
Published
1985
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5. Specificity of esterases and structure of prodrug esters. II. Hydrolytic regeneration behavior of 5-fluoro-2'-deoxyuridine (FUdR) from 3',5'-diesters of FUdR with rat tissue homogenates and plasma in relation to their antitumor activity.

Author

Kawaguchi T, Saito M, Suzuki Y, Nambu N, and Nagai T

Subjects
Animals, Esterases metabolism, Floxuridine metabolism, Floxuridine pharmacology, Hydrolysis, Male, Mice, Mice, Inbred Strains, Rats, Rats, Inbred Strains, Tissue Distribution, Floxuridine analogs & derivatives
Published
1985
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