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In this study, Ag/Zn2TiO4powder with uniform size (< 50 nm) and a specific surface area of 16.16 m2g−1was synthesized by sol–gel method and coated on enamel tiles to investigate its antibacterial activity against Escherichia coliand Staphylococcus aureus.Results obtained from XRD patterns and the curve fitting of XPS spectra revealed that silver metal and its oxides are presented in the synthesized powder. The enamel tiles coated by Ag/Zn2TiO4exhibited good antibacterial activity against both bacteria. Besides, the Ag/Zn2TiO4coating improved the surface mechanical properties of the enamel tiles.