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[Display omitted] • Prepare a novel hierarchical structured cathode for aqueous zinc batteries. • The hierarchical cathode shows ultra-long cycle life. • Nanorod arrays on the hierarchical cathode regulate the local electric field. • Tip effect accumulates protons near the surface to inhibit the side reaction. Vanadium-based oxides are promising cathode candidates for aqueous zinc batteries, but their cycling stability is unsatisfactory. Herein, a unique hierarchical structured zinc vanadate material, with amorphous nanorod arrays standing on crystalline lamellar plates, is produced by the in-situ electrochemical conditioning from a H 0.39 V 2 O 5 precursor. The hierarchical cathode achieves a high capacity of 536 mAh/g at 0.1 A/g and 344 mAh/g at 5 A/g. Importantly, a long life of 10,000 cycles with 88% capacity retention is realized at 5 A/g. Finite-element analysis shows that the tip effect of the nanorod arrays accumulates protons near the surface of the hierarchical cathode. The resulting locally low-pH environment prevents vanadium dissolution and formation of inactive Zn 3 V 2 O 7 (OH) 2 ·nH 2 O during cycling, which ensures the high cycling stability. This work presents insights into local pH regulation to optimize the cycling stability of cathode materials in aqueous zinc batteries. [ABSTRACT FROM AUTHOR]

• Breakthrough nanoplatform to enhance local therapy and inhibit metastasis in triple negative breast cancer. • Utilizing ultrasound, photoacoustic, and magnetic resonance imaging techniques for precise guidance of tumor treatment. • Novel strategy for early diagnosis and synergistic treatment of triple negative breast cancer. Triple negative breast cancer (TNBC) is a subtype of breast cancer with high invasiveness and the worst prognosis. Immunotherapy has demonstrated significant potential in its treatment. However, the response rate remains unsatisfactory. In this work, we prepared multifunctional theranostic nanoplatforms (P-R@P/U-V) with synergetic ferroptosis and photothermal therapy (PTT) in improving TNBC tumor microenvironment for improving local treatment in situ, and synergistic anti-programmed cell death-ligand 1 (PD-L1) immunotherapy to prevent distant metastasis. With P-R@P/U-V, real-time monitoring of the specific distribution in tumors is possible due to the greatly improved ultrasound imaging (US), photoacoustic imaging (PAI), and magnetic resonance imaging (MRI) capabilities. Moreover, P-R@P/U-V has excellent photothermal conversion ability. Whereas PTT killed TNBC cells after laser irradiation, the liquid–gas phase transition not only improved US but also triggered controllable release of RSL3 in situ, enhancing ferroptosis of TNBC cells. Besides, the release of tumor-associated antigens (TAAs) increased via PTT and ferroptosis, strongly stimulating T cell activation, dendritic cell maturation, and anti-tumor cytokine secretion. The lung metastases of TNBC were significantly inhibited following the combined use of P-R@P/U-V and PD-L1 inhibitors. The multimodal and multifunctional nanoplatforms demonstrated excellent effects in early diagnosis and synergistic treatment of TNBC. This represents a novel strategy based on local treatment for additional enhanced anti-PD-L1 immunotherapy, with high clinical application prospects. [ABSTRACT FROM AUTHOR]