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Your search keyword '"Joakim Andréasson"' showing total 5 results
Start Over Author "Joakim Andréasson" Journal chemical communications (cambridge, england)
5 results on '"Joakim Andréasson"'

1. Design and development of a photoswitchable DFG-out kinase inhibitor

Author

Liliana Håversen, Thomas Lundbäck, Joakim Andréasson, Morten Grøtli, Chunxia Gao, and Yongjin Xu

Subjects
chemistry.chemical_classification, Molecular Structure, Kinase, Metals and Alloys, food and beverages, General Chemistry, Living cell, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Enzyme, HEK293 Cells, Biochemistry, chemistry, Drug Development, Materials Chemistry, Ceramics and Composites, Humans, Azo Compounds, Protein Kinase Inhibitors, Protein Kinases
Abstract

A photoswitchable DFG-out kinase inhibitor has been developed. The activity of the inhibitor can efficiently be regulated by light in both enzymatic and living cell assays.

Published
2021

2. A simplicity-guided cocktail approach toward multicolor fluorescent systems

Author

Joakim Andréasson, Shiming Li, and Gaowa Naren

Subjects
Materials science, business.industry, Energy transfer, Metals and Alloys, General Chemistry, Fluorescence, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, Photochromism, Light source, Diarylethene, chemistry, Color changes, Excited state, Materials Chemistry, Ceramics and Composites, Optoelectronics, business
Abstract

A molecular cocktail containing two photochromic diarylethene derivatives that displays multicolor emission spanning blue-green to orange in a color-correlated fashion has been devised. The function does not rely on excited state communication such as energy transfer reactions, which is the typical case for similar systems. Instead, harnessing the intrinsic fluorescent and photochromic properties of the two individual diarylethene derivatives run in parallel is enough to realize the color changes. This offers an extremely flexible situation as for the choice of the fluorophores and their respective concentrations. The function is conveniently demonstrated in bulk solution at μM concentrations, where a single light source serves as the color changing stimulus.

Published
2020

3. Multi-color emission with orthogonal input triggers from a diarylethene pyrene-OTHO organogelator cocktail

Author

Chien-Wei Hsu, Henrik Sundén, Mark Douglas Johnstone, Nicolas Hochbaum, and Joakim Andréasson

Subjects
Materials science, Metals and Alloys, Supramolecular chemistry, General Chemistry, Smart material, Photochemistry, Fluorescence, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Photochromism, chemistry.chemical_compound, chemistry, Diarylethene, Phase (matter), Materials Chemistry, Ceramics and Composites, Pyrene, Derivative (chemistry)
Abstract

Controlling spectral and physicochemical properties with external stimuli is vital for the development of smart materials. Here we demonstrate a supramolecular gelator based on a fluorescent oxotriphenylhexanoate (OTHO) that can switch emission profiles between the solution and gel phase. Furthermore, a cocktail of the gelator and a photochromic diarylethene derivative enables four distinct emissive states to be obtained, which are modulated with light and heat as orthogonal input triggers.

Published
2019

4. Light-induced cytotoxicity of a photochromic spiropyran

Author

Björn Önfelt, Jesper R. Nilsson, Shiming Li, and Joakim Andréasson

Subjects
Indoles, Light, Color, 010402 general chemistry, Photochemistry, 01 natural sciences, Catalysis, Photochromism, chemistry.chemical_compound, photocontrol, Materials Chemistry, Humans, Benzopyrans, Cytotoxicity, Spiropyran, Photosensitizing Agents, Photoswitch, 010405 organic chemistry, Chemistry, lock-in detection, Cell Membrane, Metals and Alloys, apoptosis, Biological Transport, General Chemistry, Nitro Compounds, Fluorescence, proteins, switch, 3. Good health, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Water soluble, HEK293 Cells, Chemical Sciences, Ceramics and Composites, Light induced, nanoparticles, fluorescence, living cells
Abstract

In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.

Published
2011

5. Molecular AND-logic for dually controlled activation of a DNA-binding spiropyran

Author

Per Lincoln, Joakim Andréasson, Shiming Li, Martin Hammarson, and Johanna Andersson

Subjects
Models, Molecular, Indoles, Ultraviolet Rays, Intercalation (chemistry), light-activation, Antineoplastic Agents, 010402 general chemistry, Photochemistry, 01 natural sciences, Physical Chemistry, Catalysis, Photochromism, chemistry.chemical_compound, DNA-binding, Materials Chemistry, molecular logic, A-DNA, Benzopyrans, Binding site, Spiropyran, DNA recognition, Binding Sites, Photoswitch, 010405 organic chemistry, Metals and Alloys, General Chemistry, DNA, photochromism, Nitro Compounds, Combinatorial chemistry, Intercalating Agents, 0104 chemical sciences, 3. Good health, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, Ceramics and Composites, AND gate
Abstract

A spiropyran photoswitch is activated using UV light and protons from a form that shows no interaction with DNA to a form that binds to DNA by intercalation. This scheme is interpreted as a biologically relevant logic AND gate with potential applications as a dually controlled anticancer drug.

Published
2010

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