1. A PANI supported lipid bilayer that contains NhaA transporter proteins provides a basis for a biomimetic biocapacitor
- Author
-
Landry Gayet, Abderrahim Boualam, Awatef Ben Tahar, Philippe Cinquin, Jean-Pierre Alcaraz, Abdelkader Zebda, Donald K. Martin, Systèmes Nanobiotechnologiques et Biomimétiques (TIMC-IMAG-SyNaBi), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), and Gestes Medico-chirurgicaux Assistés par Ordinateur (TIMC-IMAG-GMCAO)
- Subjects
[SDV.BIO]Life Sciences [q-bio]/Biotechnology ,Biomimetic membranes ,Sodium-Hydrogen Exchangers ,Lipid Bilayers ,Biosensing Techniques ,010402 general chemistry ,01 natural sciences ,Catalysis ,chemistry.chemical_compound ,Biomimetic Materials ,Polyaniline ,Materials Chemistry ,Lipid bilayer ,Electrodes ,ComputingMilieux_MISCELLANEOUS ,Ion transporter ,High turnover ,Aniline Compounds ,010405 organic chemistry ,Escherichia coli Proteins ,Metals and Alloys ,Transporter ,General Chemistry ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Membrane ,chemistry ,Dielectric Spectroscopy ,Ceramics and Composites ,Biophysics ,Gold - Abstract
We designed a supported lipid bilayer (SLB) biomimetic membrane system that comprised polyaniline (PANI) to support a lipid bilayer membrane that incorporated Na+/H+ transporter proteins (NhaA) to give the system the capability of controllable electrogenic ion transport. The high turnover rate of NhaA (∼105 per min) provides the basis for this PANI-SLB-NhaA system to be a high-speed rechargeable biocapacitor that functions as a low-energy-consuming fast switch for biological engineering applications.
- Published
- 2019