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Your search keyword '"Zonghai Sheng"' showing total 4 results
Start Over Author "Zonghai Sheng" Journal chemical communications
4 results on '"Zonghai Sheng"'

1. pH-sensitive loaded retinal/indocyanine green micelles as an 'all-in-one' theranostic agent for multi-modal imaging in vivo guided cellular senescence-photothermal synergistic therapy

Author

Yifan Ma, Ping Li, Chen Sun, Lintao Cai, Lipeng Zhu, Zonghai Sheng, Mengze Xu, Jie Liu, Yubin Liu, Zhen Yuan, Qi Zhao, Duyang Gao, Ruibing Wang, and Xin Chen

Subjects
Indocyanine Green, genetic structures, Cellular senescence, 010402 general chemistry, Multimodal Imaging, 01 natural sciences, Micelle, Theranostic Nanomedicine, Catalysis, chemistry.chemical_compound, In vivo, Neoplasms, Materials Chemistry, medicine, Humans, Cellular Senescence, Micelles, 010405 organic chemistry, Metals and Alloys, Cancer, Retinal, General Chemistry, Hydrogen-Ion Concentration, Phototherapy, Photothermal therapy, medicine.disease, In vitro, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, Retinaldehyde, Ceramics and Composites, Biophysics, Indocyanine green
Abstract

In this study, pH-sensitive loaded retinal/indocyanine green (ICG) micelles were developed to realize novel approaches for cellular senescence-photothermal synergistic therapy to treat cancer. The micelles could enable effective multi-modal imaging in vivo guided therapy and show anticancer activity in vitro and in vivo with satisfactory biosafety.

Published
2019

2. One-step synthesis of peptide-programmed QDs as ready-to-use nanoprobes

Author

Pengfei Zhang, Dehong Hu, Lintao Cai, Jianhai Chen, Chunlei Wu, Duyang Gao, Zonghai Sheng, Jia Jing, and Ping Gong

Subjects
Cell Survival, Surface Properties, Antineoplastic Agents, Nanotechnology, Peptide, Catalysis, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Quantum Dots, PEG ratio, Materials Chemistry, Humans, Particle Size, Peptide sequence, Fluorescent Dyes, chemistry.chemical_classification, Dose-Response Relationship, Drug, Chemistry, technology, industry, and agriculture, Metals and Alloys, General Chemistry, Fluorescence, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Quantum dot, Ceramics and Composites, Nanoparticles, Drug Screening Assays, Antitumor, Peptides, Biological imaging, Ethylene glycol, Conjugate
Abstract

We developed a facile one-step method to produce ready-to-use quantum dots based on a peptide sequence containing a hexahistidine(his6-tag), poly(ethylene glycol) (PEG), and a functional group, which lead to stable and customized peptide-QDs conjugates that could serve as fluorescent nanoprobes for biological imaging and detection.

Published
2013

3. Cation exchange in aptamer-conjugated CdSe nanoclusters: a novel fluorescence signal amplification for cancer cell detection

Author

Zonghai Sheng, Shuhui Liu, Pengfei Zhang, Ping Gong, Duyang Gao, Lintao Cai, and Dehong Hu

Subjects
Microscopy, Confocal, Chemistry, Aptamer, Metals and Alloys, Nanotechnology, General Chemistry, Aptamers, Nucleotide, Conjugated system, Fluorescence, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Nanoclusters, Ion Exchange, Quantum dot, Cations, Cell Line, Tumor, Quantum Dots, Cancer cell, Cadmium Compounds, Materials Chemistry, Ceramics and Composites, Humans, Selenium Compounds, Signal amplification
Abstract

Fluorescence signal amplification by cation exchange in aptamer-conjugated CdSe nanoclusters, a biological self-assembly of CdSe quantum dots, was developed as a novel method for cancer cell detection.

Published
2012

4. Quantum dots-gold(III)-based indirect fluorescence immunoassay for high-throughput screening of APP.

Author

Zonghai Sheng, Heyou Han, Dehong Hu, Jiangong Liang, Qigai He, Meilin Jin, Rui Zhoub, and Huanchun Chenb

Subjects
*QUANTUM dots, *IMMUNOASSAY, *FLUORESCENCE quenching, *GOLD nanoparticles, *IMMUNOGLOBULIN G, *BIOCONJUGATES, *SENSITIVITY & specificity (Statistics)
Abstract

Here we report a indirect fluorescence immunoassay for high-throughput screening of APP based on the fluorescence quenching of quantum dots by gold(III), which were dissolved from gold nanoparticles-Rabbit anti-Pig IgG conjugate, and further utilize this system to detect APP in pig serum with high sensitivity and specificity. [ABSTRACT FROM AUTHOR]

Published
2009
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