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Your search keyword '"Yiqing Lin"' showing total 4 results
Start Over Author "Yiqing Lin" Journal chemical communications
4 results on '"Yiqing Lin"'

1. Absolute configuration determination of pharmaceutical crystalline powders by MicroED via chiral salt formation

Author

Bo Wang, Jessica F. Bruhn, Asmerom Weldeab, Timothy S. Wilson, Philip T. McGilvray, Michael Mashore, Qiong Song, Giovanna Scapin, and Yiqing Lin

Subjects
Materials Chemistry, Metals and Alloys, Ceramics and Composites, General Chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials
Abstract

One can confidently assign the absolute configuration of a chiral molecule using crystalline powders, via microcrystal electron diffraction (MicroED) analysis.

Published
2022
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2. Absolute configuration determination of SMTP-7 via microcrystal electron diffraction (MicroED)

Author

Bo Wang and Yiqing Lin

Subjects
Materials Chemistry, Metals and Alloys, Ceramics and Composites, General Chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials
Abstract

The absolute configuration of a clinically important drug candidate, SMTP-7, with only micron-sized powders available, is directly obtained via microcrystal electron diffraction (MicroED) analysis.

Published
2022
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3. Spirocyclic helical compounds as binding agents for bulged RNA, including HIV-2 TAR

Author

Irving H. Goldberg, Graham B. Jones, Na Zhang, Yiqing Lin, and Ziwei Xiao

Subjects
Models, Molecular, Stereochemistry, medicine.drug_class, Human immunodeficiency virus (HIV), medicine.disease_cause, Catalysis, Tar (tobacco residue), Materials Chemistry, medicine, Humans, Spiro Compounds, Fucose, HIV Long Terminal Repeat, Molecular Structure, Chemistry, Metals and Alloys, RNA, General Chemistry, Combinatorial chemistry, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, HIV-2, Ceramics and Composites, Proton NMR, RNA, Viral, Antiviral drug
Abstract

Based on fluorescence binding studies and 1D 1H NMR studies, designed synthetic analogues of NCSi-gb bind specifically with two-base bulged RNA, including HIV-2 TAR RNA, making them potential lead compounds for antiviral drug development.

Published
2006
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