1. A new triazine based π-conjugated mesoporous 2D covalent organic framework: itsin vitroanticancer activities
- Author
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Sabuj Kanti Das, Krishna Das Saha, Supratim Mahapatra, Utpal Kayal, Sasanka Dalapati, Gour P. Das, Asim Bhaumik, Snehasis Mishra, Amani A Mostafa, and Krishnendu Manna
- Subjects
Condensation polymer ,Macromolecular Substances ,Antineoplastic Agents ,Apoptosis ,02 engineering and technology ,Conjugated system ,010402 general chemistry ,01 natural sciences ,Catalysis ,chemistry.chemical_compound ,Benzene Derivatives ,Materials Chemistry ,Humans ,Benzene ,Triazine ,Membrane Potential, Mitochondrial ,Molecular Structure ,Triazines ,Hexagonal crystal system ,Chemistry ,Metals and Alloys ,General Chemistry ,HCT116 Cells ,021001 nanoscience & nanotechnology ,Combinatorial chemistry ,In vitro ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Ceramics and Composites ,Tumor Suppressor Protein p53 ,Reactive Oxygen Species ,0210 nano-technology ,Mesoporous material ,Porosity ,Covalent organic framework - Abstract
We report a new highly crystalline 2D π-conjugated hexagonal mesoporous covalent organic framework material, TrzCOF, through the solvothermal polycondensation of 1,3,5-tri(4-formylbiphenyl) benzene [Ph7(CHO)3, TFBPB] with 2,4,6-tris(4-aminophenyl)-1,3,5-triazine (TAPT) and it displayed excellent anticancer activity for human colorectal carcinoma HCT-116 cells.
- Published
- 2018
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