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Start Over Author "Peng, Ling" Journal chemical communications
11 results on '"Peng, Ling"'

4. A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging

Author

Ding, Ling, primary, Lyu, Zhenbin, additional, Tintaru, Aura, additional, Laurini, Erik, additional, Marson, Domenico, additional, Louis, Beatrice, additional, Bouhlel, Ahlem, additional, Balasse, Laure, additional, Fernandez, Samantha, additional, Garrigue, Philippe, additional, Mas, Eric, additional, Giorgio, Suzanne, additional, Pricl, Sabrina, additional, Guillet, Benjamin, additional, and Peng, Ling, additional

Published
2020
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10. Polycationic dendrimers interact with RNA molecules: polyamine dendrimers inhibit the catalytic activity of CandidaribozymesElectronic supplementary information (ESI) available: Details of dendrimer synthesis, ribozyme activity assay and gel-mobility-shift assay. See http://www.rsc.org/suppdata/cc/b4/b414241a/

Author

Wu, Jiangyu, Zhou, Jiehua, Qu, Fanqi, Bao, Penghui, Zhang, Yi, and Peng, Ling

Abstract

Various polyamine dendrimers with a triethanolamine core inhibit the activity of the Candidaribozyme by forming RNA–dendrimer complexes viaelectrostatic interactions.

Published
2005
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11. Novel triazole nucleoside analogues promote anticancer activity via both apoptosis and autophagy

Author

Xiaoxuan Liu, Yanhua Zhang, Juan L Iovanna, Xi Liu, Yun Lin, Baoping Lian, Wenjun Lan, Ling Peng, Yi Xia, Chongqing University [Chongqing], ABiMS - Informatique et bioinformatique = Analysis and Bioinformatics for Marine Science (ABIMS), Fédération de recherche de Roscoff (FR2424), Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), China Pharmaceutical University (CPU), Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), ABiMS - Informatique et bioinformatique = Analysis and Bioinformatics for Marine Science (FR2424), China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, Ctr Adv Pharmaceut & Biomat, Nanjing 210009, Peoples R China, and PENG, Ling

Subjects
Programmed cell death, [CHIM.THER] Chemical Sciences/Medicinal Chemistry, [SDV]Life Sciences [q-bio], Triazole, Antineoplastic Agents, Apoptosis, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Catalysis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Heat Shock Transcription Factors, Cell Line, Tumor, Autophagy, Materials Chemistry, Humans, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, 0303 health sciences, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Metals and Alloys, Nucleosides, General Chemistry, Triazoles, 3. Good health, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, Biochemistry, 030220 oncology & carcinogenesis, Ceramics and Composites, Microtubule-Associated Proteins, Nucleoside
Abstract

International audience; Novel nucleoside derivatives were developed using the strategy of “terminal N,N-dimethylation” to impart tertiary amines to a 1,2,4-triazole nucleoside. The obtained lead compounds displayed significantly improved anticancer activity with dual mechanisms of cell death via apoptosis and autophagy, offering a fresh perspective to searching for new anticancer candidates.

Published
2020
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