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Start Over Author "Panshu Song" Journal chemical communications
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1. A label-free and sensitive fluorescent method for the detection of uracil-DNA glycosylase activity.

Author

Jing Tao, Panshu Song, Sato, Yusuke, Nishizawa, Seiichi, Teramae, Norio, Aijun Tong, and Yu Xiang

Subjects
*URACIL-DNA glycosylase, *DNA glycosylases, *ENZYMES, *DEOXYRIBOSE, *PYRIMIDINES, *CHEMICAL reactions, *FLUORESCENT antibody technique
Abstract

The activity of uracil-DNA glycosylase (UDG), an enzyme in the base excision repair, is detected at a high sensitivity by a DNA substrate containing only one uracil through a label-free fluorescent approach, which is also successfully applied for the measurement of UDG inhibitors. [ABSTRACT FROM AUTHOR]

Published
2015
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