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Start Over Author "Jan A. Verschoor" Journal chemical communications
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1. Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a gold electrode: a potential impedimetric immunosensing platform for active tuberculosisElectronic supplementary information (ESI) available: Detailed experimental information, comparative cyclic voltammograms and Nyquist plots of bare Au, Au–MEODA and Au–MEODA–MA; Nyquist plots of HIV−–TB−serum; degree of inhibition vs.HIV+–TB+serum concentrations. See DOI: 10.1039/b905192a

Author

Nsovo S. Mathebula, Jeseelan Pillay, Gianna Toschi, Jan A. Verschoor, and Kenneth I. Ozoemena

Subjects
MOLECULAR self-assembly, IMMUNOGLOBULINS, HYDROXY acids, ANTIGENS, ELECTRODES, GOLD compounds, TUBERCULOSIS, HIV
Abstract

Electrochemical impedimetric recognition by anti-mycolic acid antibodies, present in tuberculosis (TB)-positive human serum co-infected with human immunodeficiency virus (HIV), of mycolic acids (MA) integrated into a self-assembled monolayer of N-(2-mercaptoethyl)octadecanamide on a gold electrode is described, proving that the MA-based electrode can satisfactorily discriminate between a TB-positive and a TB-negative serum, thus offering promise as a potential impedimetric immunosensing platform for active tuberculosis. [ABSTRACT FROM AUTHOR]

Published
2009
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