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Your search keyword '"Guangmei Han"' showing total 2 results
Start Over Author "Guangmei Han" Journal chemical communications
2 results on '"Guangmei Han"'

1. Revealing the signaling regulation of hydrogen peroxide to cell pyroptosis using a ratiometric fluorescent probe in living cells

Author

Ruilong Zhang, Guanqing Yang, Dong Wang, Ming-Yong Han, Xiaohe Tian, Guangmei Han, Zhongping Zhang, Tong Zhu, Bianhua Liu, and Zhengjie Liu

Subjects
Cell Survival, Cell, 010402 general chemistry, 01 natural sciences, Catalysis, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Pyroptosis, Materials Chemistry, medicine, Humans, Molecule, Hydrogen peroxide, Fluorescent Dyes, 030304 developmental biology, 0303 health sciences, Hydrogen peroxide metabolism, Chemistry, Metals and Alloys, Hydrogen Peroxide, General Chemistry, Fluorescence, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Cell biology, medicine.anatomical_structure, Cell culture, Ceramics and Composites, Signal transduction, Signal Transduction
Abstract

A ratiometric fluorescent probe with a large emission shift was developed for the accurate measurement of hydrogen peroxide (H2O2) in sophisticated pyroptosis signaling pathways. The results reported here demonstrate that H2O2, as a principal member of ROS, is a critical upstream signaling molecule in regulating pyroptosis.

Published
2021
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2. A chemically reactive Raman probe for ultrasensitively monitoring and imaging the in vivo generation of femtomolar oxidative species as induced by anti-tumor drugs in living cells

Author

Changlong Jiang, Renyong Liu, Zhongping Zhang, and Guangmei Han

Subjects
Silver, Reactive oxygen species metabolism, Metal Nanoparticles, Antineoplastic Agents, Biosensing Techniques, Oxidative phosphorylation, Spectrum Analysis, Raman, Catalysis, Polyethylene Glycols, symbols.namesake, In vivo, Cell Line, Tumor, Materials Chemistry, Humans, Metal nanoparticles, Fluorescent Dyes, chemistry.chemical_classification, Reactive oxygen species, Molecular Structure, Rhodamines, Chemistry, Metals and Alloys, General Chemistry, Molecular biology, Anti-Tumor Drugs, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Cell culture, Ceramics and Composites, Biophysics, symbols, Reactive Oxygen Species, Raman spectroscopy, HeLa Cells
Abstract

A chemically reactive Raman probe has been developed for ultrasensitively monitoring and imaging the in vivo generation of femtomolar oxidative species as induced by anti-tumor drugs in living cells.

Published
2013
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