1. Small molecule anion transporters display in vitro antimicrobial activity against clinically relevant bacterial strains
- Author
-
Carlos Rumbo, Daniel Alonso-Carrillo, Marcin Mielczarek, Ángel Del Pozo, Roberto Quesada, Marta Pastor, María García-Valverde, Israel Carreira-Barral, and Enara Herran
- Subjects
Acinetobacter baumannii ,Methicillin-Resistant Staphylococcus aureus ,Erythrocytes ,Indoles ,Klebsiella pneumoniae ,Enterococcus faecium ,Chemistry, Organic ,Microbial Sensitivity Tests ,medicine.disease_cause ,Hemolysis ,Catalysis ,Microbiology ,Materials Chemistry ,medicine ,Animals ,Pyrroles ,Ionophores ,biology ,Chemistry ,Pseudomonas aeruginosa ,Hemagglutination ,Metals and Alloys ,Química orgánica ,General Chemistry ,Antimicrobial ,biology.organism_classification ,Small molecule ,Transmembrane protein ,In vitro ,Anti-Bacterial Agents ,Rats ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Ceramics and Composites - Abstract
Highly active transmembrane anion transporters have demonstrated their activity against antibiotic-resistant and clinically relevant bacterial strains. This type of compound offers promise as a strategy to develop novel antibacterial agents.
- Published
- 2019
- Full Text
- View/download PDF