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Your search keyword '"Paolino, Marco"' showing total 2 results
Start Over Author "Paolino, Marco" Search Limiters Peer Reviewed Publication Year Range Last 10 years Journal chemical communications
2 results on '"Paolino, Marco"'

2. Dendrimeric tetravalent ligands for the serotonin-gated ion channel.

Author

Paolino, Marco, Giuliani, Germano, Anzini, Maurizio, Donati, Alessandro, Cappelli, Andrea, Mennuni, Laura, Lanza, Marco, Caselli, Gianfranco, Galimberti, Chiara, and Menziani, Maria Cristina

Subjects
*DENDRIMERS, *MULTIVALENT molecules, *MOLECULAR structure of ligands, *LIGAND-gated ion channels, *SEROTONIN receptors
Abstract

Multivalency is widely used in nature in specific recognition processes. This paper describes an approach to multivalency in the pentameric 5-HT3 receptor, a ligand-gated ion channel, which constitutes an example of intrinsically multivalent biological receptors. Owing to the picomolar Ki value, TETRA-L represents an outstanding multivalent ligand for the neurotransmitter receptor. [ABSTRACT FROM AUTHOR]

Published
2014
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