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Radical‐initiated difunctionalization of alkenes is one of the most important methods in organic synthesis and medicinal chemistry, which can be applied to synthesize value complex compounds as well as structural motifs that found in bioactive natural products and pharmaceuticals. In recent years, impressive progress have been made in this area with ideal silver catalysis. Here, we summarize recent advances in silver‐mediated radical difunctionalization of alkenes for the formation of diverse bonds, including 1) two‐component radical difunctionalization reactions enabled by an intramolecular cyclization process toward various cyclic compounds and 2) three‐component radical difunctionalization reactions leading to complex linear compounds. These silver‐mediated radical alkene difunctionalization transformations are general initiated by different radicals, such as carbon‐, oxygen‐, sulfur‐, phosphinyl‐, and halogen‐center radicals, followed by terminated with nucleophiles to form two new bonds in a single reaction. [ABSTRACT FROM AUTHOR]

We cover the achievements and thought process that have emerged as a result of the recent use of iron salts as catalysts for the oxidative coupling, addition, and functionalization on constructing C−C bonds, C−N bonds, C−O bonds, C−S bonds, and C−P bonds. These transformations concomitantly require a stoichiometric oxidant to activate the catalyst: The low-cost and ubiquity of peroxides is often used as a result of their high oxidative reactivity, resulting in the widespread utilizations of iron catalysis through the initiation of radical processes. Here, we summarize the formation of diverse chemical bonds by using iron oxidative catalysis strategies, including 1) the oxidative coupling strategy and 2) the oxidative addition and functionalization strategy. The oxidative coupling strategy focuses on the formation of one chemical bond in a single reaction, whereas the oxidative addition and functionalization strategy includes the transformations that construct at least two chemical bonds. [ABSTRACT FROM AUTHOR]