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Objective: Advanced ovarian cancer is a lethal disease. More than 75% of women with ovarian cancer are diagnosed in advanced stage FIGO IIIC-IV. The combination of surgical cytoreduction without residual tumor, and chemotherapy is the only way to prolong overall survival of women with advanced ovarian cancer., Design: Systematic review., Subject and Methods: Current literature review., Conclusion: Due to frequent involvement of the diaphragm in women with advanced ovarian cancer and the effort of optimal debulking is the inclusion of diaphragmatic surgery necessary for so affected women. Diaphragmatic surgery increases the rates of optimal cytoreduction, improves survival of women with advanced ovarian cancer and has acceptable morbidity rate.

Objective: The most of gynecological cancers are diagnosed in postmenopausal period. There are, however, part of the premenopausal women which occurs to develop vegetative problems after medical procedures. The aim of the study is to provide an overview of the current status and views on hormone replacement therapy in women after treatment for gynecologic malignancy., Subject: Systematic review., Methods: Current literature review., Conclusion: The available literature sources don't show that hormone replacement therapy for premenopausal women worsens the prognosis of the underlying disease after treatment of gynecological cancer. The limiting factor in most of the works are small groups of patients and the low stage of disease at enrollment (especially for endometrial cancer). Even though no study has shown worsening prognosis or shorter disease free interval. However, it is necessary to proceed individually for each patient with an evaluation of the current status and potential benefits that this treatment can get.