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Introduction: Among eating disorders, the binge eating is the most common disorder with prevalence to 7,8%. It is frequently connected with overweight, or obesity. Current treatment of binge eating is based on psychotherapy, pharmacotherapy and regime approach. Recently, repetitive transcranial magnetic stimulation appears as hopeful therapeutic method, for example used with success as an alternative therapy to treatment of resistant major depresion. Because of its non-invasiveness, good tolerability and minimal side effects, new options of its use are studied. It seems to be a promising therapeutic method for treatment of eating disorders. Dorsolateral prefrontal cortex is considered as main experimental target of stimulation for treatment of binge eating disorder. The target of study was to prove that rTMS can significantly reduce craving for food in patients with binge eating disorder. Methods: Study was conceived randomized double-blind placebo controlled. The active group was stimulated by highfrequency rTMS, with stimulation parameters: frequency 10Hz, 1500 pulses, 107s inter-train, 100% minimal motor threshold and 10 sessions of stimulation. The control grooup was stimulated by sham rTMS coil. Both groups completed FCQ-S and FCQ-T questionnaire before stimulation, after 10. session and one month after 10. session. Results: We noticed statistically significant decrease of craving in FCQ-S questionnaire after 10. session of stimulation (p = 0,0168) and non-significant decrease after a month (p = 0,2184). For FCQ-T questionnaire, the change in craving was significant in both cases, after 10. session and after a month (p = 0,0114, p = 0,0368). When we compared results with control group, they were insignificant, except the situation after month in FCQ-T evaluation, when in control group, craving was significantly more reduced, than in stimulated group (p = 0,0111). Conclusion: We are able to tell, that the therapy by high-frequency rTMS can significantly reduce craving among patient with binge eating disorder. However, the difference between real rTMS and sham rTMS group was insignificant. [ABSTRACT FROM AUTHOR]

The effects of direct current on central nervous system, today known as transcranial direct current stimulation is a method not entirely unknown among biological treatments in psychiatry. It is a perspective tool for the modulation of brain activity, applicable in the research of cortical representations of sensomotorical, cognitive and other functions of various neuronal networks as well as in the treatment of many neuropsychiatric disorders. There has been an increase in the number of studies in the past few years, especially those dealing with major depressive disorders where this method has proven itself to be a promising biological treatment method in ameliorating pathological mood. It is a safe method with very few side effects if following safety protocols. [ABSTRACT FROM AUTHOR]

Anorexia nervosa is a serious, often lifethreatening, disease that belongs to eating disorders, a group of diseases characterized by pathological eating behavior that need to be understood and treated throughout the bio-psycho-socio-spiritual context. Despite all clinical and research efforts, treatment outcome (the combination of regimens, psychopharmacotherapy and psychotherapy) is not satisfactory, and other therapeutic options must be sought. In recent years, the number of studies of neuromodulation in psychiatric and neurological diseases has been increasing. We can divide these methods into invasive, minimally invasive and non-invasive methods, non-invasive group including transcranial DC stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), chronobiotherapeutic modalities, and more. In the available studies, tDCS appears to be a safe and well-tolerated method in the treatment of mental anorexia (AN). The studies are based on the hypothesis that stimulation of the dorsolateral prefrontal cortex (DLPFC), which is important for emotional regulation, reduces the need for dietary behavior, either by direct action on the regulation of food intake or translocation, or by influencing comorbid psychopathology. [ABSTRACT FROM AUTHOR]