1. Obstructive sleep apnea is frequent in patients with hypertensive intracerebral hemorrhage and is related to perihematoma edema.
- Author
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Pontes-Neto OM, Fernandes RM, Sander HH, da Silva LA, Mariano DC, Nobre F, Simão G, de Araujo DB, dos Santos AC, and Leite JP
- Subjects
- Acute Disease, Aged, Brain Edema diagnostic imaging, Female, Hematoma diagnostic imaging, Humans, Intracranial Hemorrhage, Hypertensive diagnostic imaging, Logistic Models, Male, Middle Aged, Odds Ratio, Polysomnography, Prospective Studies, Risk Assessment, Risk Factors, Severity of Illness Index, Sleep Apnea, Obstructive diagnosis, Time Factors, Tomography, X-Ray Computed, Brain Edema etiology, Hematoma etiology, Intracranial Hemorrhage, Hypertensive complications, Sleep Apnea, Obstructive etiology
- Abstract
Background: Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension. We hypothesize that OSA is frequent in patients with acute hypertensive intracerebral hemorrhage (ICH) and is related to the perihematoma edema., Methods: Thirty-two non-comatose patients with a hypertensive ICH underwent polysomnography in the acute phase. Perihematoma edema volume was measured on CT scans at admission, after 24 h (early control) and after 4-5 days (late control). The Spearman coefficient (r(s)) was used for correlations., Results: OSA occurred in 19 (59.4%) patients. The apnea-hypopnea index was correlated with relative edema at admission CT (r(s) = 0.40; p = 0.031), early CT (r(s) = 0.46; p = 0.011) and at late CT (r(s) = 0.59; p = 0.006)., Conclusions: OSA is highly frequent during the acute phase of hypertensive ICH and is related to perihematoma edema.
- Published
- 2010
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