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The effect of low-intensity laser irradiation on pigment cells cultured by chorioallantoic method was studied. Laser irradiation influenced the cell shapes and sizes of the pigment cells. Metabolically, this treatment increased thymidine uptake and incorporation but reduced those of leucine. The phagocytic activity as measured by latex particles uptake was not affected. It was concluded that the biological effect of laser irradiation on cell cultures depends on the dose applied, the individual tissue and other factors.

The alkaline phosphatase and DNA-RNA activities in the retinas of young and old albino mice were determined histochemically after photic exposure. Different patterns between the two age groups were obtained for the alkaline phosphatase reaction before and after photic exposure. In the young animals, more retinal layers showed increased activity after exposure whereas in the old animals, the converse was true. DNA-RNA reaction revealed decreased DNA activities in the old animals 30 h after exposure. The results were also correlated with biochemical studies on the uptake of 2-deoxyglucose, dopamine and leucine.