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Start Over Author "Cerar, Andraz" Journal cell transplantation
3 results on '"Cerar, Andraz"'

2. Transendocardial CD34+Cell Transplantation in Noncompaction Cardiomyopathy: First-in-Man Case Study

Author

Cerar, Andraz, Zemljic, Gregor, Frljak, Sabina, Jaklic, Martina, Poglajen, Gregor, Sever, Matjaz, Cukjati, Marko, and Vrtovec, Bojan

Abstract

Noncompaction cardiomyopathy is a rare congenital heart disorder characterized by an arrest of the myocardial compaction process. This results in the altered formation of coronary microvessels with a resulting decrease in myocardial perfusion. Transendocardial CD34+cell transplantation has been shown to increase myocardial perfusion and function in patients with non-ischemic heart failure. In our first-in-man case study, we investigated the feasibility, safety and clinical effect of transendocardial CD34+cell therapy in a patient with noncompaction cardiomyopathy.

Published
2018
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3. Transendocardial CD34 + Cell Transplantation in Noncompaction Cardiomyopathy: First-in-Man Case Study.

Author

Cerar A, Zemljic G, Frljak S, Jaklic M, Poglajen G, Sever M, Cukjati M, and Vrtovec B

Subjects
Adult, Cardiomyopathies diagnostic imaging, Cardiomyopathies physiopathology, Echocardiography, Endocardium cytology, Endocardium diagnostic imaging, Endocardium physiopathology, Female, Heart diagnostic imaging, Heart physiopathology, Humans, Magnetic Resonance Imaging, Antigens, CD34 analysis, Cardiomyopathies therapy, Stem Cell Transplantation methods, Stem Cells cytology
Abstract

Noncompaction cardiomyopathy is a rare congenital heart disorder characterized by an arrest of the myocardial compaction process. This results in the altered formation of coronary microvessels with a resulting decrease in myocardial perfusion. Transendocardial CD34 + cell transplantation has been shown to increase myocardial perfusion and function in patients with non-ischemic heart failure. In our first-in-man case study, we investigated the feasibility, safety and clinical effect of transendocardial CD34 + cell therapy in a patient with noncompaction cardiomyopathy.

Published
2018
Full Text
View/download PDF

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