1. RETRACTED: Heritable Integration of kDNA Minicircle Sequences from Trypanosoma cruzi into the Avian Genome: Insights into Human Chagas Disease
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Antonio R. L. Teixeira, Marian R D'Souza-Ault, Rubens J. Nascimento, Liana Lauria-Pires, Clever Gomes, Ana de Cássia Rosa, Nadjar Nitz, and Francisco Moreno
- Subjects
Chagas disease ,Host genome ,biology ,Biochemistry, Genetics and Molecular Biology(all) ,digestive, oral, and skin physiology ,Minicircle ,medicine.disease ,biology.organism_classification ,Genome ,Virology ,General Biochemistry, Genetics and Molecular Biology ,Original data ,Evolutionary biology ,medicine ,Trypanosoma cruzi ,Sequence (medicine) ,Southern blot - Abstract
This article has been retracted at the request of the Editors: Reason: "It has been brought to our attention that there are concerns with the integration site sequence analyses provided in support of integration of T. cruzi kDNA into the host genome in this paper. Following careful and extensive review of the data by independent experts in the field, we are forced to conclude that the sequence analyses associated with publication do not provide strong evidence for the central hypothesis and are open to alternative intepretations. The Southern blot analyses, while consistent with integration, do not in themselves provide sufficiently strong support for the main conclusion. We are therefore retracting the paper. The authors of the paper stand by the original data and do not endorse the retraction."
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