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Your search keyword '"Calcium compounds -- Research"' showing total 3 results
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3 results on '"Calcium compounds -- Research"'

1. The latest waves in calcium signaling

Author

Montell, Craig

Subjects
Protein binding -- Research, Calcium compounds -- Research, Homeostasis -- Research, Biological sciences
Abstract

The contributions of Ca(super 2+) and Ca(super 2+) binding proteins to health and disease were addressed in a meeting held in April 2005 in Bnaff, Canada. Insights got from the mechanical studies offered the potential for new therapeutic approaches to combat a variety of diseases resulting from alterations in Ca(super 2+) homeostasis.

Published
2005

2. Cleavage of the plasma membrane Na+/Ca(super 2)+ exchanger in excitotoxicity

Author

Bano, Daniele, Young, Kenneth W., Guerin, Christopher J., LeFeuvre, Ros, Rothwell, Nancy J., Luigi, Naldini, RIzzuto, Rosario, Carafoli, Ernesto, and Nicotera, Pierluigi

Subjects
Calcium compounds -- Research, Sodium compounds -- Research, Cerebral ischemia -- Research, Cell membranes -- Research, Biological sciences
Abstract

The major plasma membrane Ca(super 2)+ extruding system, the Na+/Ca(super 2)+ exchanger (NCX) that is cleared during brain ischemia and in neurons undergoing excitotoxicity is described. Proteolytic inactivation of NCX-driven neuronal Ca(super 2)+ extrusion is responsible for the delayed excitotoxic Ca(super 2)+ deregulation and neuronal death.

Published
2005

3. Neuroprotection in Ischemia: Blocking calcium-permeable acid-sensing ion channels

Author

Zhi-Gang Xiong, Xiang-Ping Chu, Xiao-Man Zhu, Minami, Manabu, Hey, Jessica, Wen-Li Wei, MacDonald, John F., Price, Margaret P., Wemmie, John A., Welsh, Michael J., and Simon Roger P.

Subjects
Calcium compounds -- Research, Acidosis -- Research, Ischemia -- Research, Biological sciences
Abstract

Ca(super 2+) toxicity remains the central focus of ischemic brain injury, and acidosis is a common feature of ischemia. The study shows that acidosis activates Ca(super 2+)-permeable acid-sensing ion channels (ASICs).

Published
2004

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