1. Prevalence and prognostic impact of hsCRP elevation are age‐dependent in women but not in men undergoing percutaneous coronary intervention
- Author
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George Dangas, Nitin Barman, Samin K. Sharma, Usman Baber, Sebastian Kelle, Jason C. Kovacic, Prakash Krishnan, Anastasios Roumeliotis, Samantha Sartori, Rishi Chandiramani, Roxana Mehran, Moritz Blum, Davide Cao, Niklas Beyhoff, Joseph Sweeny, Ridhima Goel, and Annapoorna Kini
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Population ,030204 cardiovascular system & hematology ,Coronary artery disease ,03 medical and health sciences ,Percutaneous Coronary Intervention ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Prevalence ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,education ,education.field_of_study ,Proportional hazards model ,business.industry ,nutritional and metabolic diseases ,Percutaneous coronary intervention ,General Medicine ,Middle Aged ,Prognosis ,medicine.disease ,C-Reactive Protein ,Treatment Outcome ,Quartile ,Conventional PCI ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,Mace - Abstract
BACKGROUND High-sensitivity C-reactive protein (hsCRP) predicts outcomes after percutaneous coronary intervention (PCI). OBJECTIVE We studied the prevalence and prognostic impact of hsCRP elevation according to age in men and women undergoing PCI. METHODS We included patients undergoing PCI at our center from 2010 until 2017, excluding those with myocardial infarction (MI) on presentation, neoplastic disease and hsCRP >10 mg/L at baseline. Elevated hsCRP was defined as >3 mg/L. The outcome of interest was major adverse cardiac events (MACE) consisting of all-cause death, MI and target vessel revascularization. The association between hsCRP elevation and outcomes was assessed using adjusted Cox models. RESULTS 10,432 men and 4,345 women were included. Elevation of hsCRP was present in 25.7% of men and 37.0% of women (p
- Published
- 2020