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Your search keyword '"Antonio Montefusco"' showing total 2 results
Start Over Author "Antonio Montefusco" Journal catheterization and cardiovascular interventions
2 results on '"Antonio Montefusco"'

1. Impact of an optical coherence tomography guided approach in acute coronary syndromes: A propensity matched analysis from the international FORMIDABLE-CARDIOGROUP IV and USZ registry

Author

Roberto Garbo, Giuseppe Biondi-Zoccai, Maurizio D'Amico, Maurizio Bertaina, Fabrizio D'Ascenzo, Thomas F. Lüscher, Gennaro Sardella, Claudio Moretti, Konstantinos Toutouzas, Pascal Meieir, Giacomo Boccuzzi, Mario Iannaccone, Pascal Motreff, Antonio Montefusco, Géraud Souteyrand, Christian Templin, Massimo Mancone, Nicolas Amabile, Fiorenzo Gaita, Corrado Tamburino, Pierluigi Omedè, Fabrizio Ugo, Giampaolo Niccoli, Francesco Colombo, and Antonio H. Frangieh

Subjects
medicine.medical_specialty, Acute coronary syndrome, business.industry, medicine.medical_treatment, Percutaneous coronary intervention, Stent, Retrospective cohort study, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Coronary thrombosis, Drug-eluting stent, Internal medicine, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, 030212 general & internal medicine, Myocardial infarction, Cardiology and Cardiovascular Medicine, business, Mace
Abstract

AIM To determine the potential clinical impact of OCT (Optical Coherence Tomography) during primary percutaneous coronary intervention in patients presenting with ACS (Acute Coronary Syndrome). METHODS AND RESULTS FORMIDABLE is a multicentre retrospective registry enrolling all patients presenting with ACS and treated with an OCT-guided approach, while the USZ registry enrolled patients treated with a standard angiography guided approach. Multivariate adjustment was performed via a propensity score matching. The number stents useds was the primary outcome, while the incidence of MACE (a composite of death, myocardial infarction, target vessel revascularization, and stent thrombosis) was the secondary endpoint. A total of 285 patients OCT-guided and 1,547 angiography guided patients were enrolled, resulting in 270 for each cohort after propensity score with matching. Two stents were used in 12% versus 34%; 3 stents in 8% versus 38% of the patients (P

Published
2016

2. Outcomes of patients with low-pressure aortic gradient undergoing transcatheter aortic valve implantation

Author

Claudio Moretti, Maurizio D'Amico, Fabian Nietlispach, Federico Conrotto, Marco Pavani, Giuseppe Biondi-Zoccai, Pierluigi Omedè, Fabrizio D'Ascenzo, Francesco Maisano, Fiorenzo Gaita, Antonio Montefusco, Paolo Scacciatella, University of Zurich, and Conrotto, Federico

Subjects
Male, Time Factors, 030204 cardiovascular system & hematology, Cochrane Library, Coronary artery disease, 0302 clinical medicine, Risk Factors, Nuclear Medicine and Imaging, 80 and over, Odds Ratio, Clinical endpoint, 030212 general & internal medicine, Aged, 80 and over, education.field_of_study, Ejection fraction, General Medicine, Treatment Outcome, Aortic Valve, Meta-analysis, Aortic valve stenosis, 10209 Clinic for Cardiology, Cardiology, ventricular function, Female, aortic valve stenosis, left, prognosis, transcatheter aortic valve replacement, Aortic Valve Stenosis, Chi-Square Distribution, Humans, Risk Assessment, Hemodynamics, Transcatheter Aortic Valve Replacement, Radiology, Nuclear Medicine and Imaging, Cardiology and Cardiovascular Medicine, Radiology, medicine.medical_specialty, Population, 610 Medicine & health, 2705 Cardiology and Cardiovascular Medicine, 03 medical and health sciences, Internal medicine, medicine, 2741 Radiology, Nuclear Medicine and Imaging, Radiology, Nuclear Medicine and imaging, education, Aged, business.industry, medicine.disease, 10020 Clinic for Cardiac Surgery, Surgery, Stenosis, business
Abstract

Background: The risk/benefit balance of transcatheter aortic valve implantation (TAVI) in patients with low-gradient aortic stenosis (LGAS) remains to be well defined. Aim of the study was to investigate the impact of LGAS in patients undergoing TAVI. Methods: Medline, Cochrane Library, and Scopus were searched for articles reporting outcome of patients with LGAS undergoing TAVI. The primary endpoint was 12-months all-cause mortality and the secondary endpoint was 30-day all-cause mortality. Using event-rates as dependent variable, a meta-regression was performed to test for interaction between baseline clinical features (age, gender, diabetes mellitus, coronary artery disease, left ventricular ejection fraction (LVEF) and type of implanted valve) and transaortic gradient for the primary endpoint. Results: Eight studies with a total of 12,589 patients were included. Almost one-third of the patients presented with LGAS (27.3%: 24.4–29.2). Median LVEF was 48% in patients with LGAS and 56% in patients with high-gradient AS. Patients with LGAS were more likely to have diabetes mellitus, previous coronary artery disease, higher mean Logistic EuroSCORE, and lower EF. At 12 (12–16.6) months, low transaortic gradient emerged as independently associated with all-cause death, both if evaluated as a dichotomous and continuous value (respectively OR 1.17; 1.11–1.23 and OR 1.02; 1–1.04, all CI 95%). Clinical variables, including EF did not affect this result. Conclusions: In a population of TAVI patients, LGAS appears to be independently related to dismal prognosis. © 2016 Wiley Periodicals, Inc.

Published
2016

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