1. A malignant eccrine spiradenoma of the scalp
- Author
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Mat Griffiths and Whitney T.H. Chow
- Subjects
Adult ,Male ,Surgical margin ,Pathology ,medicine.medical_specialty ,Skin Neoplasms ,animal structures ,medicine.medical_treatment ,Eccrine Glands ,Article ,Lesion ,Rare Diseases ,medicine ,Atypia ,Humans ,Neoplasm Invasiveness ,Pelvis ,Neoplasm Staging ,Scalp ,Adenoma, Sweat Gland ,business.industry ,Wide local excision ,Biopsy, Needle ,Head and neck cancer ,Histology ,General Medicine ,medicine.disease ,Immunohistochemistry ,Sweat Gland Neoplasms ,Treatment Outcome ,medicine.anatomical_structure ,medicine.symptom ,Tomography, X-Ray Computed ,business ,Follow-Up Studies - Abstract
Malignant eccrine spiradenoma (MES) is an extremely rare but aggressive tumour, resulting in high mortality. We report the first case in the UK of metastatic MES on the scalp of a 37-year-old man who initially presented with a raised nodular mass which had grown rapidly over a few months. Excision biopsy of the lesion was performed and histology confirmed MES with evidence of cytological atypia and necrosis. A further wide local excision of the lesion with a 1 cm surgical margin was performed and full clearance was achieved. At 10-month follow-up another similar lesion had developed close to the previously excised area. A CT scan demonstrated metastatic lesions in the lungs, liver and pelvis, and subsequently chemotherapy was initiated. Although MES is uncommon, it has a high propensity to metastasise, therefore prompt identification, treatment and close follow-up of these tumours is essential.
- Published
- 2014
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