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1. Diagnostic pathway to amyotrophic lateral sclerosis (ALS): the significance of Babinski's sign in a unique patient and the necessity for a multidisciplinary approach

Author

Marielle C.G. Vlooswijk, Henk van Santbrink, Olaf E. M. G. Schijns, and Vincent J Bulthuis

Subjects
Male, medicine.medical_specialty, Pediatrics, Neurology, medicine.diagnostic_test, business.industry, Amyotrophic Lateral Sclerosis, Neurooncology, Physical examination, General Medicine, Middle Aged, medicine.disease, Article, Reflex, Babinski, Diagnosis, Differential, Physical therapy, Gemistocytic Astrocytoma, Humans, Medicine, Medical diagnosis, Amyotrophic lateral sclerosis, Differential diagnosis, business, Motor neurone disease
Abstract

In this case report, we present a patient with rare diagnosis of amyotrophic lateral sclerosis (ALS). In this patient, four different neurological disorders were diagnosed in a short-time period of 8 months. The first three diagnoses, chronic low back and leg pain, a left frontal gemistocytic astrocytoma WHO grade 2 and suspected Lyme's disease, could not fully explain the signs of physical examination. Finally, the diagnosis of ALS could reduce these signs to the same denominator.

Published
2013
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