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A recent study conducted by researchers at the University of Houston explores the role of AKAP12 (A kinase anchoring protein 12) in heart failure. The study found that AKAP12 upregulation is associated with accelerated cardiac dysfunction through the AKAP12-PDE8 axis. The researchers used various methods, including live cell imaging and mouse models, to investigate the effects of AKAP12 on cardiac function. The findings suggest that AKAP12 may be a potential target for pharmacological interventions in heart failure. [Extracted from the article]