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Aims: Coronary slow flow (CSF) phenomenon is described by angiographically normal coronary arteries with delayed opacification of the distal vasculature. Studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-Te) may correspond to the transmural dispersion of repolarization and that increased Tp-Te interval and Tp-Te/QT ratio are associated with malignant ventricular arrhythmias. The aim of this study was to evaluate ventricular repolarization by using Tp-Te interval and Tp-Te/QT ratio in patients with CSF.Materials and Method: This study included 50 CSF patients (40 male, mean age 48,6±12,5 years) and 40 control person (23 male, mean age 47,8±12,5 years). Tp-Te interval and Tp-Te/QT ratio were measured from the 12-lead electrocardiogram. These parameters were compared between groupsResults: Baseline characteristics of the study groups were comparable. In electrocardiographic parameters analysis, QT and corrected QT were similar in CSF patients compared to the controls (357±35,2 vs 362±38,0 milliseconds and 419±25,8 vs 430±44,2 milliseconds, all p value >0,05). Tp-Te interval, Tp-Te/QT and Tp-Te/QTc ratio were significantly higher in CSF patients (85±13,7 vs 74±9,9 milliseconds and 0,24±0,03 vs 0,20±0,02 and 0,20±0,03 vs 0,17±0,02 all P value <0,001).Conclusion: Our study revealed that QTd, Tp-Te interval and Tp-Te/QT ratio are prolonged in patients with CSF.Table 1.Comparison of data in coronary slow flow patients and controlsCSF group ( N=50)Control (n=40)p valueAge (year)48,6±12,547,8±12,5NSHypertension (%)10 (20%)26 ( 65%)NSDiabetes Mellitus (%)3 (6%)3 (7,5%)NSDyslipidemia (%)19 (38%)6 (15%)0,029HDL-Cholesterol (mg/dL)41±10,451±14.10,001Mean frame count23±5,0419±1,7<0,001LAD20± 5,417±1,5<0,001Cx24±7,820±2,4=0,006RCA26±8,719±1,7<0,001Tp-Te/QT ratio0,24±0,030,20±0,02<0,001Tp-Te/QTc ratio0,20±0,030,17±0,02<0,001LVEF (%)60±3,560±2,4NS [ABSTRACT FROM AUTHOR]

Aim: Coronary artery ectasia (CAE) is commonly defined as local or generalized dilatation of a coronary vessel up to 1,5 times the diameter of an adjacent vessel. Tp-Te interval and Tp-Te/QT ratio have emerged as a novel electrocardiographic (ECG) markers of increased dispersion of ventricular repolarization. The aim of this study was to evaluate ventricular repolarization by using Tp-Te interval and Tp-Te/QT ratio in patients with CAE.Materials and methods: Patient records were retrospectively analyzed. ECG of 28 patients, who were diagnosed as CAE were obtained and scanned.Tp-Te, QT and corrected QT intervals and some other ECG intervals were measured. ECGs of age and sex matched 22 healthy control individuals were also analyzed for comparison.Results: Baseline characteristics and QT, QTc intervals were similar in both group. Tp-Te (97,71±8,7 vs 85,23±7,1; p<0,001) and Tp-Te/QT (0,22±0,0 vs 0,20±0,0; p<0,001) were significantly worse in CAE group.Conclusions: :Tp-Te is a measure of transmural dispersion of repolarization in the left ventricle and accepted as a surrogate for increased ventricular arrhythmogenesis risk. Tp-Te and Tp-Te/QT are relatively new markers which also indicate repolarization defects. Our results show that CAE patients significantly higher values of Tp-Te and Tp-Te/QT than controls. These measurements may indicate increased arrhythmogenesis risk for individuals with CAE.ParametersPatientsControlsp valueLVEDD (mm)45±843±100.59LVESD (mm)28±526±60.48LVEF (%)62.9±4.465.9±5.10.03QT max383.43±30375.91±230.35QTc max421.32±26409.95±180.09TPe97.71±8.785.23±7.1<0.001TPe/QT ratio0.22±0.00.20±0.0<0.001QT disp26.89±9.924.41±6.50.31Echocardiographic and electrocardiographic parameters between the patient group with the control group. [ABSTRACT FROM PUBLISHER]