1. Admission blood glucose and 10-year mortality among patients with or without pre-existing diabetes mellitus hospitalized with heart failure
- Author
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Yoel Toledano, Gregory Golovchiner, Osnat Itzhaki Ben Zadok, Yitschak Biton, Ehud Kadmon, Alexander Omelchenko, Tuvia Ben Gal, Ilan Goldenberg, Alon Barsheshet, Robert Klempfner, Enrique Z. Fisman, Ran Kornowski, and Alexander Tenenbaum
- Subjects
Blood Glucose ,Male ,lcsh:Diseases of the circulatory (Cardiovascular) system ,medicine.medical_specialty ,Time Factors ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,030204 cardiovascular system & hematology ,Continuous variable ,03 medical and health sciences ,0302 clinical medicine ,Patient Admission ,Diabetes mellitus ,Internal medicine ,medicine ,Humans ,In patient ,Hospital Mortality ,Prospective Studies ,Angiology ,Aged ,Original Investigation ,Aged, 80 and over ,Heart Failure ,Proportional hazards model ,business.industry ,Admission blood glucose ,medicine.disease ,Prognosis ,Hospitalization ,lcsh:RC666-701 ,Heart failure ,Pre-existing diabetes mellitus ,Female ,Cardiology and Cardiovascular Medicine ,business ,Follow-Up Studies - Abstract
Background High admission blood glucose (ABG) level has been associated with a poor short-term outcome among non-diabetic patients with heart failure (HF). We aimed to investigate the association between ABG levels and long-term (10 years) mortality in patients with or without pre-existing diabetes mellitus (DM) admitted with HF. Methods We analyzed data on 1811 patients with DM and 2182 patients without pre-existing DM who were hospitalized with HF during a prospective national survey. The relationship between ABG and 10-year mortality was assessed using the Cox proportional hazard model adjusting for multiple variables. ABG was analyzed both as a categorical (200 mg/dL) and as a continuous variable. Results At 10 years of follow-up the cumulative probability of mortality was 85 and 78% among patients with DM and patients with no pre-existing DM (p 200 mg/dL had an increased mortality risk (>200 mg/dL versus 200 mg/dL is associated with increased mortality risk.
- Published
- 2017