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Your search keyword '"Takao Kato"' showing total 2 results
2 results on '"Takao Kato"'

1. Low 1,5-anhydroglucitol levels are associated with long-term cardiac mortality in acute coronary syndrome patients with hemoglobin A1c levels less than 7.0%

Author

Shohei Ouchi, Kazunori Shimada, Tetsuro Miyazaki, Shuhei Takahashi, Yurina Sugita, Megumi Shimizu, Azusa Murata, Tomoyasu Kadoguchi, Takao Kato, Tatsuro Aikawa, Shoko Suda, Eiryu Sai, Masaru Hiki, Hiroshi Iwata, Takatoshi Kasai, Katsumi Miyauchi, and Hiroyuki Daida

Subjects
1,5-anhydroglucitol, Diabetes mellitus, Postprandial hyperglycemia, Acute coronary syndrome, Cardiac mortality, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Diabetes mellitus is considered an important risk factor for cardiovascular diseases. High hemoglobin A1c (HbA1c) levels, which indicate poor glycemic control, have been associated with occurrence of cardiovascular diseases. There are few parameters which can predict cardiovascular risk in patients with well-controlled diabetes. Low 1,5-anhydroglucitol (1,5-AG) levels are considered a clinical marker of postprandial hyperglycemia. We hypothesized that low 1,5-AG levels could predict long-term mortality in acute coronary syndrome (ACS) patients with relatively low HbA1c levels. Methods The present study followed a retrospective observational study design. We enrolled 388 consecutive patients with ACS admitted to the cardiac intensive care unit at the Juntendo University Hospital from January 2011 to December 2013. Levels of 1,5-AG were measured immediately before emergency coronary angiography. Patients with early stent thrombosis, no significant coronary artery stenosis, malignancy, liver cirrhosis, a history of gastrectomy, current steroid treatment, moderately to severely reduced kidney function (estimated glomerular filtration rate

Published
2017
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2. Low 1,5-anhydroglucitol levels are associated with long-term cardiac mortality in acute coronary syndrome patients with hemoglobin A1c levels less than 7.0%

Author

Hiroshi Iwata, Shuhei Takahashi, Kazunori Shimada, Hiroyuki Daida, Megumi Shimizu, Shohei Ouchi, Yurina Sugita, Takatoshi Kasai, Katsumi Miyauchi, Azusa Murata, Shoko Suda, Tomoyasu Kadoguchi, Tetsuro Miyazaki, Takao Kato, Eiryu Sai, Masaru Hiki, and Tatsuro Aikawa

Subjects
Blood Glucose, Male, lcsh:Diseases of the circulatory (Cardiovascular) system, Time Factors, Endocrinology, Diabetes and Metabolism, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Coronary Angiography, Hospitals, University, chemistry.chemical_compound, 0302 clinical medicine, Diabetes mellitus, Japan, Risk Factors, Cause of Death, Medicine, Original Investigation, Aged, 80 and over, Hazard ratio, Cardiac mortality, Middle Aged, Postprandial Period, Postprandial, Cardiology, 1,5-Anhydroglucitol, Female, Acute coronary syndrome, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Renal function, Down-Regulation, 030209 endocrinology & metabolism, Deoxyglucose, Disease-Free Survival, Postprandial hyperglycemia, 03 medical and health sciences, Internal medicine, Humans, Risk factor, 1,5-anhydroglucitol, Aged, Proportional Hazards Models, Retrospective Studies, Glycated Hemoglobin, Chi-Square Distribution, business.industry, medicine.disease, chemistry, lcsh:RC666-701, Hyperglycemia, Multivariate Analysis, Coronary care unit, business, Biomarkers
Abstract

Background Diabetes mellitus is considered an important risk factor for cardiovascular diseases. High hemoglobin A1c (HbA1c) levels, which indicate poor glycemic control, have been associated with occurrence of cardiovascular diseases. There are few parameters which can predict cardiovascular risk in patients with well-controlled diabetes. Low 1,5-anhydroglucitol (1,5-AG) levels are considered a clinical marker of postprandial hyperglycemia. We hypothesized that low 1,5-AG levels could predict long-term mortality in acute coronary syndrome (ACS) patients with relatively low HbA1c levels. Methods The present study followed a retrospective observational study design. We enrolled 388 consecutive patients with ACS admitted to the cardiac intensive care unit at the Juntendo University Hospital from January 2011 to December 2013. Levels of 1,5-AG were measured immediately before emergency coronary angiography. Patients with early stent thrombosis, no significant coronary artery stenosis, malignancy, liver cirrhosis, a history of gastrectomy, current steroid treatment, moderately to severely reduced kidney function (estimated glomerular filtration rate

Published
2017

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